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Arun Kumar Singh, Meenakshi Dhanawat - Neuroinflammation and Biomarker Discovery, Häftad

Häftad, Engelska, 2027

Neuroinflammation and Biomarker Discovery

From Mechanisms to Clinical Application

Av Arun Kumar Singh, Meenakshi Dhanawat

2649 kr

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Beskrivning
Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

  • Explains neuroinflammatory mechanisms at molecular and cellular levels
  • Connects research findings to clinical diagnostics and therapeutic strategies
  • Provides disease-specific biomarker profiles for neurodegenerative and autoimmune disorders
  • Highlights cutting-edge imaging platforms for biomarker discovery
Produktinformation
  • Utgivningsdatum: 2027-03-01
  • Mått: 152 x 229 x undefined mm
  • Format: Häftad
  • Språk: Engelska
  • Antal sidor: 350
  • Förlag: Elsevier Science
  • ISBN: 9780443485299
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Arun Kumar Singh is Assistant Professor in the Department of Pharmacy at the University School of Pharmaceutical Sciences, Rayat Bahra University, Sahauran, India. His research interests include nano-formulation, cancer biology, and neuroscience, alongside digital and computational approaches such as machine learning, artificial intelligence, big data analytics, blockchain, and the Internet of Things. He has contributed academic books, book chapters, and review articles in pharmaceutical sciences and healthcare technology, with a focus on interdisciplinary approaches that integrate pharmaceutical research with emerging digital technologies.Meenakshi Dhanawat is Associate Professor at the Amity Institute of Pharmacy, Amity University Haryana, India. Her research spans medicinal chemistry, synthetic and heterocyclic chemistry, nanotechnology, drug delivery systems, prodrug design, complexation, polymer chemistry, and herbal drug extraction, with a particular focus on central nervous system drug delivery. Dr. Dhanawat completed her M.S. (Pharm.) from the National Institute of Pharmaceutical Education and Research (NIPER), Mohali, where her research project focused on glycosyl amino acids. She obtained her Ph.D. from the Indian Institute of Technology (IIT-BHU), Varanasi, India. She was a recipient of the Travelship Award in the DDD Section of AAPS 2010, held in California, USA. She has also received international travel grants from the Department of Biotechnology (DBT) and Department of Science and Technology (DST), Government of India, to participate in international scientific conferences in California, USA, and Munich, Germany, respectively. She has received several other fellowships and awards, including the prestigious Rajiv Gandhi National Fellowship.

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