Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

• 1. What is this book series about?- 2. Preface.- 3. Introductory chapter.- 4. Individual predispositions in healthy vasospastic individuals: Patient profiling for targeted prevention of “down-stream” pathologies as cost-effective personalised medicine.- 5. Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders.- 6. New animal models of progressive neurodegeneration: tools for developing predictive diagnostics and identifying presymptomatic therapeutic targets.- 7. Tau pathology: A selected view on the current status.- 8. The Use of Biomarkers for Prediction and Prevention of Alzheimer's and Parkinson's Diseases.- 9. Making clinical trials of Alzheimer’s disease delay-of-onset a reality by use of a prognostic genetic biomarker.- 10. An update on CSF biomarkers of Parkinson’s disease.- 11. Glaucomatous optic neuropathy: Risk assessment and potential targets for effective prevention and treatments tailored to the patient.- 12. Toward a personalized approach in amyotrophic lateral sclerosis: new developments in diagnosis, genetics, pathogenesis and therapies.- 13. Recent advances in ALS research: perspectives for personalized clinical application.- 14. Exercise in Multiple Sclerosis – an Integral Component of Disease Management.- 15. Bridging the Informatics Gap between Bench and Bedside: Implications to Neurodegenerative Diseases.- 16. Personalized Medicine In Rare Paediatric Neurometabolic Diseases.

From the reviews:“This book provides an overview of up-to-date literature on existing and potential future predictive, preventive, and personalized therapeutic approaches to neurodegenerative diseases. It is a useful resource for clinicians and researchers interested in the current status of research findings and their potential future applications in this field.” (Nilufer Ertekin-Taner, Doody’s Book Reviews, October, 2013)