Neurobiology of Oxytocin

0 Behavioral Reaction Effect of Effect of Species Route of Dose of Reference - 0 oxytocin vasopressin treatment oxytocin (mol/animal) p r-' 11 Extinction of active avoidance Facilitation Opposite Rat i. p. 2x 10- SCHULZ et al. (1974, 1976); ~ (bench-jumping) reaction TELEGDY and KovAcs (1979a) 0 12 10- < Extinction of active avoidance Facilitation Opposite Rat i. c. v. BOHUS et aI. (1978b) "', 0 (pole-jumping) reaction '" 10 2 x 10- Extinction of active avoidance Delay Similar Rat s. c. WALTER et aI. (1978); (pole-jumping) behavior BoHUS et al. (1978b) 12 10- Acquisition of active avoidance Delay No effect Rat i. c. v. BoHUS et al. (1978b) (pole-jumping) behavior 11 2x 10- Acquisition of active avoidance No effect No effect Rat i. p. SCHULZ et al. (1974) (bench-jumping) behavior 10 Passive avoidance (step-down) Attenuation Opposite Rat i. p. 2x 10- KovAcs et al. (1978) behavior 13 10- Passive avoidance (step-through) Attenuation Opposite Rat i. c. v. BoHUS et al. (1978a, b); behavior KovAcs and DE WmD (1983) 14 2. 5 x 10- Passive avoidance (step-through) Attenuation Opposite Rat Hippocampus, KovAcs et al.(1979) behavior dorsal raphe 14 Passive avoidance (step-through) Facilitation Similar Rat Septum 2. 5 x 10- KovAcs et al. (1979) behavior 8 10- Passive avoidance (choice No effect No effect Rat ? SAGHAL and WRIGHT (1984) measure) 7 Attenuation of puromycin- 10- No effect Effective Mouse s. c WALTER et al.