Neurobiology of Obsessive-Compulsive Disorder

  • Nyhet

Häftad, Engelska, 2026

Av Eric A. Storch, Sameer Anil Sheth, Wayne K. Goodman, Eric A Storch, Wayne K Goodman

1 969 kr

Kommande

Neurobiology of Obsessive-Compulsive Disorder provides a comprehensive review of obsessive-compulsive disorder through a neurobiological lens, offering invaluable insights for researchers and clinicians alike. This book begins with a comprehensive introduction to OCD, detailing its definition, historical perspectives, prevalence, and symptomatology, alongside its comorbidities and associated disorders. Delving into the genetic and familial aspects, it examines genetic predispositions, heritability, and significant genome-wide association studies. The text also addresses neuropsychological findings, cognitive dysfunctions, and the implications for treatment, alongside neurodevelopmental factors, including early life stress, immune system dysregulation, and environmental risk factors. Special attention is given to PANDAS/PANS as mechanisms of OCD pathogenesis and the insights gained from animal models. Subsequent chapters cover diagnosis, pharmacological treatments, and a range of psychotherapeutic and behavioral interventions, including CBT, ERP, and ACT, as well as neuromodulation techniques. Finally, the book presents neurobiology-informed treatment approaches, personalized medicine, and integrative strategies, concluding with discussions on current challenges, ethical considerations, and future research directions. This comprehensive guide is essential for advancing the understanding and treatment of OCD.

  • Reviews the definition of OCD, historical perspectives, prevalence, symptomatology, and comorbidities
  • Explores the genetic predispositions, heritability, and brain regions implicated in OCD
  • Examines the roles of serotonin, dopamine, glutamate, and other neurotransmitters in the neurochemistry of OCD
  • Covers pharmacological treatments, psychotherapeutic and behavioral interventions, including CBT, ERP, and neuromodulation techniques
  • Discusses current research challenges, ethical considerations, promising research avenues, and future directions in the neurobiological treatment of OCD

Produktinformation

  • Utgivningsdatum2026-06-01
  • Mått152 x 229 x undefined mm
  • Vikt450 g
  • FormatHäftad
  • SpråkEngelska
  • SerieNeurobiology of Disease
  • Antal sidor270
  • FörlagElsevier Science
  • ISBN9780443274466

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