Neurobiology of Aging

Exploring Cognitive Decline and Neurodegeneration

Häftad, Engelska, 2025

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Neurobiology of Aging: Exploring Cognitive Decline and Neurodegeneration is a comprehensive reference exploring the complexities of the aging brain. This book examines the intricate processes driving cognitive decline and neurodegeneration. From the gradual loss of neurons and synapses to the formation of protein aggregates characteristic of Alzheimer's disease, each chapter reviews key aspects of brain aging. Chapters dissect the mechanisms driving neuronal loss, synaptic dysfunction, and protein misfolding, shedding light on the intricate interplay of oxidative stress, inflammation, and mitochondrial dysfunction. This book also navigates through strategies for healthy brain aging, from the impact of diet and exercise to the role of cognitive stimulation.

Reviews the complex interplay of various molecular, cellular, and systemic processes that contribute to cognitive decline and neurodegeneration
Discusses genetic influences on aging and neurodegenerative diseases
Outlines various therapeutic approaches to age-related cognitive decline and neurodegenerative diseases

Produktinformation

Utgivningsdatum2025-12-08
Mått216 x 276 x 20 mm
Vikt450 g
FormatHäftad
SpråkEngelska
Antal sidor342
FörlagElsevier Science
ISBN9780443362958

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik
Reproduktionsmedicin inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin

Dr. Sachchida Nand Rai is an Assistant Professor at University Centre for Research & Development (UCRD), Chandigarh University, Punjab, India. He obtained his MSc in Biochemistry from Purvanchal University, India, and his PhD in Biochemistry from Banaras Hindu University, India. Dr. Rai researches the anti-oxidative and anti-neuroinflammatory properties of phytochemicals for the treatment of neurodegenerative diseases. He is a lifetime member of the Indian Academy of Neuroscience.

Part 1: Mechanisms of Brain Aging1. Introduction to the Neurobiology of Aging2. Neuronal Loss and Synaptic Dysfunction3. Protein Misfolding and Aggregation and its role in dementia with Lewy bodies4. Oxidative Stress and Aging5. Inflammation: Chronic Inflammation in AgingPart 2: Factors Influencing Brain Aging6. Mitochondrial Dysfunction and Aging7. Neurotransmitter Systems in Aging8. Genetic Influences on Aging and Neurodegenerative Diseases9. Environmental and Lifestyle Factors in Brain Aging10. The Role of Diet in Brain HealthPart 3: Interventions and Strategies for Healthy Brain Aging11. Exercise and Cognitive Function in Aging12. Unlocking Cognitive Vitality: The Interplay of Stimulation, Sleep, and Brain Aging13. Exploring the Multifaceted Links Between Comorbidities and Cognitive Aging14. Therapeutic Approaches to Age-Related Cognitive Decline and Neurodegenerative Diseases15. Exploring Promising Pharmaceutical Candidates for Anti-Aging