Negative and Cognitive Symptoms in Schizophrenia

Antonio Vita is a Full Professor of Psychiatry at the University of Brescia and serves as the Head of the University Psychiatric Unit. Since 2016, he has been the Head of the Department of Mental Health and Addiction Services at the Spedali Civili Hospital in Brescia. In 2021, he assumed the position of Dean of the Faculty of Medicine and Surgery at the University of Brescia and, in 2024, that of Vice Rector at the same university. His main research activities focus on clinical, biological, pharmacological, and rehabilitative aspects of mental disorders, with particular emphasis on neuromorphological and neurofunctional correlates of psychotic disorders and on rehabilitation and cognitive remediation in schizophrenia. Prof. Vita is actively engaged in several international research networks and has authored over 300 publications published in major international scientific journals. He has held the positions of President of the Italian Society of Psychosocial Rehabilitation and is currently the President of the Italian Group for the Study and Treatment of Cognition in Psychiatry. Additionally, he serves as the President of the Section on Neuroimaging of the World Psychiatric Association and Co-Chair of the Section on Schizophrenia of the European Psychiatric Association. He is included in the Editorial Boards of various international journals and serves as the Deputy Editor of Psychiatry Research and Editor in Chief of the Section on Social Psychiatry and Psychiatric Rehabilitation of Frontiers in Psychiatry.Silvana Galderisi is a Full Professor of Psychiatry at the University of Campania Luigi Vanvitelli. She holds the Chair of the Department of Mental and Physical Health and Preventive Medicine of the same university, and she is also the Head of the Emergency Unit in the Department of Mental Health. Additionally, she serves as the Delegate of the School of Medicine and Surgery of the University of Campania "Luigi Vanvitelli" for the Schools of Specialization in the Health Area. Her main areas of research include clinical, biological, and social aspects influencing schizophrenia outcomes. Her research combines a wide range of aspects, such as genetics, neurocognition, social cognition, neuroimaging, psychopathology, and clinical psychology. Some specific research areas she focuses on are the clinical and neurobiological characterization of the deficit syndrome of schizophrenia, the pathophysiology of schizophrenia's negative symptom domains, neurocognitive impairment in psychiatric disorders, and neurocognitive rehabilitation programs for patients with psychoses. She has authored or coauthored over 400 papers in books and scientific journals.Bernardo Carpiniello is an Emeritus Professor of Psychiatry at the University of Cagliari (Italy). He has been previously been a  Full Professor of Psychiatry and  the Director of the Psychiatric Clinic at the same University. From 2000 to 2023, he was also the Director of the Postgraduate School of Psychiatry. Prof Carpiniello held various important roles in professional associations, including President of the Italian Psychiatric Association (SIP), Chair of the European Psychiatric Association Council of National Psychiatric Associations and member of the board of the Italian Society of Psychopathology (SOPSI). Prof. Carpiniello has also served as President of the Italian Academic Board of Professors, President of the Italian Society of Social Psychiatry, and President of the Italian Society of Psychiatric Rehabilitation. His main areas of research interest are clinical psychiatry, clinical psychopharmacology, social psychiatry, psychiatric epidemiology, and consultation-liaison psychiatry. He has authored or co-authored 350 papers, most of which were published in national or international peer-reviewed journals.

• .PART 1: Negative Symptoms in Schizophrenia: Clinical and Management Implications.- 1. Negative symptoms in schizophrenia: definition, classification and course.- 2. The assessment of negative symptoms in schizophrenia.- 3. Negative symptoms and psychosocial functioning in schizophrenia .- 4. Assessment of Negative symptoms and of Real-life Functioning: Critical Areas of Overlap.- 5. Negative symptoms in schizophrenia: neurobiological bases.- 6. Negative symptoms in schizophrenia: the role of pharmacotherapy .- 7. Psychological Interventions for Negative Symptoms of Schizophrenia.- .PART 2: Cognitive Impairment in Schizophrenia: Clinical and Management Implications.- 8. Cognitive Impairment in Schizophrenia: Definition, Classification and Course.- 9. Cognitive impairment and psychosocial functioning in schizophrenia.- 10. Feasible and Acceptable Approaches to Assessment of Cognitive Health Need.- 11. Cognitive Impairment in Schizophrenia: Neurobiological Bases.- 12. Pharmacological Treatment of Cognitive Impairment in Schizophrenia.- 13. Cognitive Impairment in Schizophrenia: The Role Of Cognitive Rehabilitation .- .PART 3: Negative and Cognitive Symptoms in Schizophrenia: An Integrative Perspective.- 14. Relationship between cognitive impairment and negative symptoms in schizophrenia.- 15. Negative Symptoms, Cognition and Recovery in Schizophrenia .- 16. Methodologic Considerations on Developing Drugs for Negative Symptoms and Cognitive Impairment in Schizophrenia.- 17. Physical Exercise to Improve Negative Symptoms, Cognitive Deficits, and Levels of Daily-Life Functioning in Schizophrenia Spectrum Disorders: Current Evidence and Treatment Recommendations.- 18. Cognitive Impairment and Negative Symptoms in Schizophrenia: A Summary and Future Research Perspectives.