Nanomedicine and Tissue Engineering

Robin Augustine is a research fellow working in the area of biomaterial fabrication for various medical applications. He has research experience in molecular mechanism of cancer, cytotoxicity studies and pathways that regulate the mechanism of glucose metabolism, cancer, and diabetes during his research at Rajive Gandhi Centre for Biotechnology, India. He is currently working in the area of nanobiotechnology in the lab of Professor Sabu Thomas at the International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India.Dr. Nandakumar Kalarikkal obtained his master’s degree in physics with a specialization in industrial physics and his PhD in semiconductor physics from Cochin University of Science and Technology, Kerala, India. He was a postdoctoral fellow at NIIST, Trivandrum, and later joined with Mahatma Gandhi University. Currently he is the joint director of the Centre for Nanoscience and Nanotechnology as well as assistant professor in the School of Pure and Applied Physics at Mahatma Gandhi University. His current research interests include synthesis, characterization, and applications of nanophosphors, nanoferrites, nanoferroelctrics, nanomultiferroics, nanocomposites, and phase transitions.Oluwatobi Samuel Oluwafemi, PhD, is a senior lecturer at the Department of Chemistry and Chemical Technology, Walter Sisulu University, Mthatha Campus, Eastern Cape, South Africa. He has published many papers in internationally reviewed journals and has presented at several professional meetings. He is a fellow of many professional bodies, a reviewer for many international journals, and has received many awards for his excellent work in material research. His current research interests include application of nanoparticles in medicine, water treatment, polymer, LEDs, and sensors.Joshy K. S. is a research scholar at International and Inter University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam, Kerala, India. Sabu Thomas, PhD, is a professor of polymer science and engineering at the School of Chemical Sciences and Director of the International and Inter University Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University, Kottayam, Kerala, India. He received his BSc (1980) in chemistry from the University of Kerala, BTech. (1983) in polymer science and rubber technology from the Cochin University of Science and Technology, and PhD (1987) in polymer engineering from the Indian Institute of Technology, Kharagpur. The research activities of Professor Thomas include surfaces and interfaces in multiphase polymer blend and composite systems, phase separation in polymer blends, compatibilization of immiscible polymer blends, thermoplastic elastomers, phase transitions in polymers, nanostructured polymer blends, macro-, micro- and nanocomposites, polymer rheology, recycling, reactive extrusion, processing–morphology–property relationships in multiphase polymer systems, double networking of elastomers, natural fibers and green composites, rubber vulcanization, interpenetrating polymer networks, diffusion and transport and polymer scaffolds for tissue engineering. He has supervised 65 PhD theses, 30 MPhil theses, and 40 master’s theses. He has three patents to his credit. He also received the coveted Sukumar Maithy Award for the best polymer researcher in the country for the year 2008. Very recently Professor Thomas received the MRSI and CRSI medals for his excellent work. With over 600 publications to his credit and over 17,500 citations, with an h-index of 67, Dr. Thomas has been ranked fifth in India as one of the most productive scientists.

• Preface. Nanomedicine: From Concept to Reality. Tissue Engineering: Principles, Recent Trends and the Future. Tailored Heating Superparamagnetic Nanoparticles for Hyperthermia Applications. Silver Nanoparticles: Newly Emerging Antimicrobials in the 21st Century. Tailoring Plasmon Resonances in Metal Nanospheres for Optical Diagnostics of Molecules and Cells. Recent Advances in Nanoparticulate Drug Delivery System for Antiviral Drugs. Triggerable Liposomes: Newer Approach in Cytoplasmic Drug Delivery. P-gp Inhibitors: A Potential Tool to Overcome Drug Resistance in Cancer Chemotherapy. Formulation and Evaluation of Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Oral Delivery of Ketoconazole. Recent Advances in the Application of Biopolymer Scaffolds for 3D Culture Of Cells. Electrospun Matrices for Biomedical Applications: Recent Advances. Functionalization of Scaffolds with Biomolecules for Various Types of Tissue Engineering Applications. Anti Microbial Nano Materials for Wound Dressings. Cutaneous Wound Care: Grafts to Tissue Engineered Skin Substitutes. Index.

"Provides a clear and thorough insight into the current applications of nanotechnology in medicine. With its broad scope, this book reaches topics like the use of magnetic hyperthermia for the selective destruction of cancer cells, as well as green synthesis of metal nanoparticles and the surface functionalization of nanoparticles. Equally significant, it delves into the current trends of drug delivery techniques, including various nanocarriers, a self-nanoemulsifying drug delivery system, and scaffolding techniques. It features several chapters related to tissue engineering, focusing on scaffold fabrication techniques like electrospinning, the materials used, and their applications, especially in wound dressings. Ideal for professionals in the field, the chapters contained here give an in-depth look at the current state of nanomedicine and tissue engineering, and present this information in an easily comprehensible manner." —Wenguo Cui, Professor, Orthopedic Institute, Soochow University, China