Nanomaterials as Gene and Nucleic Acid Delivery Platforms

Nyhet

Häftad, Engelska, 2026

4 019 kr

Kommande

Nanomaterials as Gene and Nucleic Acid Delivery Platforms explores the intersection between gene therapy and nanotechnology, assessing the benefits of nanoscale platforms for safe and efficient gene and nucleic acid delivery. This book addresses the growing need for alternative gene delivery methods to overcome the limitations and safety concerns associated with conventional viral vectors. Four comprehensive parts provide a holistic overview of the core concepts of gene therapy and delivery; the broad range of nanomaterials available for use as carriers; key approaches, and clinical translation of nanomaterial-based delivery platforms for gene therapy. Nanomaterials as Gene and Nucleic Acid Delivery Platforms is of use to researchers and academics in the fields of nanomaterials, biomaterials, gene therapy, molecular biology, immunology, and disease therapeutics. This book may also be of interest to clinicians researching novel materials and approaches for therapeutics.

Covers the unique and beneficial properties of a wide range of nanomaterials for gene and nucleic acid delivery, including polymers, proteins and peptides, lipids, metals, and carbon-based nanomaterials
Reviews applications of nanomaterial-based gene delivery platforms in tissue engineering, regenerative medicine, drug delivery, cancer treatment, and more
Details assay approaches and transfection factors for in vitro and in vivo use, as well as clinical translation considerations

Produktinformation

Utgivningsdatum2026-05-01
Mått152 x 229 x undefined mm
FormatHäftad
SpråkEngelska
SerieWoodhead Publishing Series in Biomaterials
Antal sidor700
FörlagElsevier Science
ISBN9780443277146

Tillhör följande kategorier

Dr Rocktotpal Konwarh is a Scientist at Baba Kinaram Research Foundation, Mau, India. He completed his PhD in Chemical Sciences from Tezpur University, India, before joining as a DBT Research Associate in Bioinformatics. He was an Institutional Post-Doctoral Fellow in Biomaterial Engineering and Nanomedicine at IIT Guwahati, India. Dr Konwarh has previously been an Assistant Professor at Addis Ababa Science and Technology University, Ethiopia, and a guest faculty member at Dibrugarh University, India, Jimma University, Ethiopia, and Mekelle University, Ethiopia. His research interests include nanomaterials and biopolymeric nanocomposites for biomedical and allied applications, tissue engineering, and targeted therapeutics delivery. He has obtained several research fellowships over the years, including the Canadian Commonwealth visiting research fellowship, University of Guelph, Canada, and the DST-UKIERI project co-investigatorship and post-doctoral visiting research fellowship to University College London, England. Dr Konwarh is an editorial board and review board member of international peer-reviewed journals and author of many highly cited journal articles, as well as a couple of book chapters.Dr. William C. Cho, Highly Cited Researchers in 2023 by Clarivate. Dr. Cho has published over 600 SCI peer-reviewed papers; he is the world's top 0.1% most influential scientists in the world.

Part 1: Introduction to Nanomaterials in Gene and Nucleic Acid Delivery1. Nanomaterials: Basics to biocargo-delivery applications2. Gene therapy: Principles, prospects, and challenges in viral and non-viral gene delivery stratagems3. Harnessing nanomaterials in gene delivery, gene therapy and genome engineering- Retrospect and prospectsPart 2: Spectrum of Nanomaterials for Gene Delivery4. Design, diversity and applications of polymeric nanomaterials in gene delivery5. Dendrimers and nanostructured hyperbranched polymers in gene delivery6. Proteins and peptide nanomaterials for gene delivery7. Polysaccharide based nanomaterials for gene delivery8. Lipid based nanomaterials in gene delivery9. Harnessing exosomes for gene delivery10. Metal based nanomaterials in nucleic acid delivery and therapy11. Carbon and silica-based nanomaterials for gene delivery12. Quantum dots as multifunctional gene delivery agents13. Trigger/stimulus-responsive nanomaterials for gene delivery14. Viruses: Prospects for nanomedicine and gene deliveryPart 3: Approaches and Considerations in Nanomaterials Mediated Gene Delivery15. Factors affecting in vitro and ex vivo transfection and in vivo gene delivery using nanomaterials16. Nanomaterials and gene expression profile modulation17. Assay approaches for in vitro and in vivo gene expression profiling18. Nanotechnology, omics science and gene therapy19. Nanomaterials and facets of epigeneticsPart 4: Key Applications and Clinical Translation20. Plant genome engineering: Prospects of nanomaterials-based gene delivery21. Gene delivery using electrospun nanobiomaterials: Implications in tissue engineering and regenerative medicine22. Nanomaterials for siRNA delivery and the gamut of applications23. Nanomaterials as CRISPR/Cas delivery platforms for genome editing24. Harnessing nanomaterials in gene therapy for cancer25. Nanomaterials for neural-specific gene therapy26. Nanotechnology in gene delivery for ophthalmic applications27. Ethics, clinical translation and safety regulations of nanomaterials in gene therapy