Myosins

A Superfamily of Molecular Motors

Inbunden, Engelska, 2020

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Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms.

Produktinformation

Utgivningsdatum2020-05-26
Mått178 x 254 x 29 mm
Vikt1 176 g
FormatInbunden
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor455
Upplaga2
FörlagSpringer Nature Switzerland AG
ISBN9783030380618

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Biologi inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik

Lynne Coluccio, PhD, began her career at Boston University as a Principal Scientist at the Boston Biomedical Research Institute (BBRI) in 1996. After the institute was closed in 2013, she became a Research Associate in the Department of Physiology & Biophysics at the Boston University School of Medicine and has remained since then. While at the BBRI, she played a variety of roles on the committee including as a chair of the Faculty Search Committee and as a member of the Public Relations Committee. Throughout her she career she has mentored dozens of students who have gone into academia, medicine, teaching, and music.

Introduction.- Myosin Structure.- Cargo Binding by Unconventional Myosins.- Cryo-EM of Actin-Myosin Structures.- Small Molecule Effectors of Myosin Function.- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction.- High-Speed Atomic Force Microscopy to Study Myosin Motility.- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches.- How Actin Tracks Affect Myosin Motors.- Myosins in the Nucleus.- Myosins in Cytokinesis.- Myosins and Disease.- Myosins and Hearing.- The Actomyosin Systems in Apicomplexa.- Approaches to Identify and Characterise MYO6-Cargo Interactions.- Class IX Myosins: Motorized RhoGAP Signaling Molecules.- Myosin X.- Myosin XVI.- Myosin XVIII.- Myosin XIX