Myogenesis in Development and Disease

Dr. David Sassoon received his Ph.D.in Biology from Columbia University (New York, NY) in 1986 for his studies on behavior and muscle/brain function. He subsequently performed his postdoctoral research at the Pasteur Institute (Paris, France) where he worked on the molecular and developmental pathway by which early lineage commitment occurs for skeletal muscle. In 1988, he was appointed Assistant Professor at Boston University Medical School (Boston, MA) and in 1992, he joined the Brookdale Center for Developmental Biology at Mt. Sinai School of Medicine-NYU where he became Full Professor. In 2006, he became a Unit Head (Chair) of an new department focused upon regenerative medicine at the INSERM-University of Pierre and Marie Curie-Sorbonne at the Pitié Hospital and continues to run a research team focused upon adult stem cells in heart, muscle and vascular tissues. He has coordinated several large multipartner consortiums based in Europe and the USA and presently is a coordinator of a Leducq Trans-Atlantic Network.

• 1. "What Did Maxwell’s Equations Really Have to Do With Edison’s Invention?": Addressing the Complexity of Developing Clinical Interventions for Skeletal Muscle DiseaseJonathan Dando2. The Muscle Stem Cell Niche in Health and DiseaseOmid Mashinchian, Addolorata Pisconti, Emmeran Le Moal and C. Florian Bentzinger3. Translational Control of the Myogenic Program in Developing, Regenerating, and Diseased Skeletal MuscleRyo Fujita and Colin Crist4. The Composition, Development, and Regeneration of Neuromuscular JunctionsWenxuan Liu and Joe V. Chakkalakal5. Cellular Biomechanics in Skeletal Muscle RegenerationEdward W. Li, Olivia C. McKee-Muir and Penney M. Gilbert6. Satellite Cell Self-RenewalLorenzo Giordani, Alice Parisi and Fabien Le Grand7. "Known Unknowns": Current Questions in Muscle Satellite Cell BiologyDawn D.W. Cornelison8. Epigenetic Regulation of Adult MyogenesisDaniel C.L. Robinson and Francis J. Dilworth9. Dysregulated Myogenesis in RhabdomyosarcomaPeter Y. Yu and Denis C. Guttridge10. Muscle Stem Cells and AgingAndrew Brack and Ara B. Hwang

Praise for the Series: "Outstanding both in variety and in the quality of its contributions." --Nature