Muscle Atrophy

Dr. Junjie Xiao is Principal Investigator and Professor at Regeneration and Ageing Lab in Shanghai University, Shanghai, China.

• An overview of muscle atrophy.- Myofibers.- Muscle mass, quality, and composition changes during atrophy and sarcopenia.- Muscle changes during atrophy.- Skeleton muscle damage in intorauterine growth restriction.- The role of IGF-1 signaling in skeletal muscle atrophy.- mTOR signaling pathway and protein synthesis: from training to aging and muscle autophagy.- Past, present and future perspective of targeting myostatin and related signaling pathways to counteract muscle atrophy.- Hormones and muscle atrophy.- Ubiquitin-proteasome pathway and muscle atrophy.- Noncoding RNAs in muscle atrophy.- NF-kB and inflammatory cytokine signalling; role in skeletal muscle atrophy.- Redox homeostasis in age-related muscle atrophy.- Disturbed Ca2+ homeostasis in muscle wasting disorders.- Muscle atrophy in cancer.- The molecular mechanisms and prevention principles of muscle atrophy in aging.- Muscle atrophy in cardiovascular diseases.- Muscle atrophy in chronic kidney diseases.- Sarcopenia in liver disease: current evidence and issues to be resolved.- Muscle atrophy measurement as assessment method for low back pain patients.- Drugs of muscle wasting and their therapeutic targets.- Nutritional support to counteract muscle atrophy.- Nutritional considerations in preventing muscle atrophy.- Physical exercise for muscle atrophy.- To contrast and reverse skeletal muscle atrophy by Full-Body In-Bed Gym, a mandatory life-style for older olds and borderline mobility impaired persons.- Overview of FES-assisted cycling approaches and their benefits on functional rehabilitation and muscle atrophy.- The reversal of atrophy in human skeletal muscles by home-based Functional Electrical Stimulation after complete SCI lower motor neuron denervation.- Preverting muscle atrophy following strokes- a reappraisal.- Muscle atrophy: present and future.