Multiparticulate Drug Delivery

Formulation, Processing and Manufacturing

Häftad, Engelska, 2018

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Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery.

Produktinformation

Utgivningsdatum2018-07-27
Mått155 x 235 x 23 mm
Vikt616 g
FormatHäftad
SpråkEngelska
SerieAdvances in Delivery Science and Technology
Antal sidor396
FörlagSpringer-Verlag New York Inc.
ISBN9781493983674

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Kemi inom Naturvetenskap och teknik

Ali Rajabi-Siahboomi is Vice President and Chief Scientific Officer at Colorcon Inc. He obtained his PhD in Pharmacy from University of Nottingham (UK). Dr. Rajabi-Siahboomi held various academic positions in Nottingham and Liverpool JM Universities (UK), before joining Colorcon. His main research interests are in the area of solid dosage form pharmaceutics and pharmaceutical technology with emphasis on oral drug delivery systems. He has published over 150 articles, book chapters, abstracts and patents.

Overview of multiparticulates.- Characterization of inert pellets for drug layering.- The science and practice of extrusion-spheronization.- Fluid bed technology, process robustness and scale-up.- Solution and suspension drug layering on inert pellets.- Dry powder layering on pellets Mini-tabs; versatile multiparticulate options for oral drug delivery.- Science and practice of microencapsulation technology.- Use of multiparticulate systems for fixed dose combination drug delivery.- Dissolution testing consideration of multiparticulate system.- Taste masking of multiparticulate systems.- Multiparticulate systems for pediatrics.- Application of methacrylic acid copolymers polymers for oral multiparticulate drug delivery.- Ethylcellulose applications on multiparticulate dosage forms.- Multi-unit particulate systems (MUPS).- In-line particle size characterization of multipartuclate systems.- In-vivo characterization of multiparticulatesystems.