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Arne Schousboe, Hans Bräuner-Osborne - Molecular Neuropharmacology, Häftad

Häftad, Engelska, 2010

Molecular Neuropharmacology

Strategies and Methods

Av Arne Schousboe, Hans Bräuner-Osborne

2169 kr

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Beskrivning
A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. By illuminating how neurons in the central nervous communicate with other, these techniques can lead to the development of novel therapeutic strategies for neurological diseases.
Produktinformation
  • Utgivningsdatum: 2010-12-16
  • Mått: 178 x 254 x undefined mm
  • Format: Häftad
  • Språk: Engelska
  • Antal sidor: 271
  • Förlag: Humana Press Inc.
  • ISBN: 9781617373848
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Recensioner i media

"I would highly recommend this book to neuroscientists, pharmacologists, and medicinal chemists who are interested in ligand-macromolecular interactions. It provides descriptions of state-of-the-art tools needed to understand how CNS neurons communicate and perspectives regarding the development of novel therapeutic drugs for neurological diseases. Each chapter is well written and concise beginning with an appropriate introduction to the topic and ending with a brief summary, conclusion, or future perspective section. The references are selective and appropriate. Special features include cutting-edge techniques for using site directed mutagenesis and molecular modeling; novel insights into the functioning of transmitter receptors and transporters; and state-of-the-art discussions on the molecular pharmacology of GABA and glutamate receptors and transmitter transporters. "-Doody's Health Sciences Book Review Journal "...provides a highly readable account...an excellent book." - ChemBioChem

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