Molecular Neuroendocrinology

Professor David Murphy, University of Bristol, UKAs part of The Molecular Neueroendocrinology Research Group, Professor Murphy uses gene discovery and transfer techniques to study the neuronal regulation of the cardiovascular system in health and disease.Dr Harold Gainer, National Institute of Neurological Disorders and Stroke (NINDS), USA Dr Gainer's research focuses on the mechanisms involved in the establishment and maintenance of specific peptidergic neuronal phenotypes in the central nervous system.

• List of Contributors, viiSeries Preface, xiAbout the Companion Website, xiiiIntroduction 1David Murphy and Harold GainerPart A Genome and Genome Expression1 Evolutionary Aspects of Physiological Function and Molecular Diversity of the Oxytocin/Vasopressin Signaling System 5Zita Liutkevicǐūtė and Christian W. Gruber2 The Neuroendocrine Genome: Neuropeptides and Related Signaling Peptides 25J. Peter H. Burbach3 Transcriptome Dynamics 57David A. Carter, Steven L. Coon, Yoav Gothilf , Charles K. Hwang, Leming Shi, P. Michael Iuvone, Stephen Hartley, James C. Mullikin, Peter Munson, Cong Fu, Samuel J. Clokie, and David C. Klein4 New Players in the Neuroendocrine System: A Journey Through the Non‐coding RNA World 75Yongping Wang, Edward A. Mead, Austin P. Thekkumthala, and Andrzej Z. Pietrzykowski5 Transcription Factors Regulating Neuroendocrine Development, Function, and Oncogenesis 97Judy M. Coulson and Matthew Concannon6 Epigenetics 121Chris MurgatroydPart B Proteins, Posttranslational Mechanisms, and Receptors7 Proteome and Peptidome Dynamics 141Lloyd D. Fricker8 Neuropeptidomics: The Characterization of Neuropeptides and Hormones in the Nervous and Neuroendocrine Systems 155Ning Yang, Samuel J. Irving, Elena V. Romanova, Jennifer W. Mitchell, Martha U. Gillette, and Jonathan V. Sweedler9 Posttranslational Processing of Secretory Proteins 171Nabil G. Seidah and Johann Guillemot10 Neuropeptide Receptors 195Stephen J. Lolait, James A. Roper, Georgina G.J. Hazell, Yunfei Li, Fiona J. Thomson, and Anne‐Marie O’CarrollPart C The Tool Kit11 Germline Transgenesis 219Jim Pickel12 Somatic Transgenesis (Viral Vectors) 243Valery Grinevich, H. Sophie Knobloch‐Bollmann, Lena C. Roth, Ferdinand Althammer,Andrii Domanskyi, Ilya A. Vinnikov, Marina Eliava, Megan Stanifer, and Steeve Boulant13 Optogenetics Enables Selective Control of Cellular Electrical Activity 275Ryuichi Nakajima, Sachiko Tsuda, Jinsook Kim, and George J. Augustine14 Non‐Mammalian Models for Neurohypophysial Peptides 301Einav Wircer, Shifra Ben‐Dor, and Gil LevkowitzPart D Case Studies – Integration and Translation15 Osmoregulation 331David Murphy, Jose Antunes‐Rodrigues, and Harold Gainer16 Food Intake, Circuitry, and Energy Metabolism 355Giles S.H. Yeo17 Stress Adaptation and the Hypothalamic‐Pituitary‐Adrenal Axis 375Greti Aguilera18 Neuroendocrine Control of Female Puberty: Genetic and Epigenetic Regulation 405Alejandro Lomniczi and Sergio R. Ojeda19 Oxytocin, Vasopressin, and Diversity in Social Behavior 423Lanikea B. King and Larry J. YoungGlossary 443Index 459