Molecular Mechanisms Influencing Aggressive Behaviours

The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

• Symposium on Molecular mechanisms influencing aggressive behaviours, held at the Novartis Foundation, London, 20-22 July. Editors :Gregory Bock (Organizer) and Jamie Goode.This meeting was based on a proposal made by Donald Pfaff, Barry Keverne and Randy Nelson.Introduction (Donald Pfaff).Some suggestions for revitalizing aggression research (Robert J. Blanchard and D. Caroline Blanchard).Aggressive behaviour: contributions from genes on the Y chromosome (Robin Lovell-Badge).Androgen receptor and molecular mechanisms of male-specific gene expression (Diane M. Robins).Quantitative trait locus analysis of aggressive behaviours in mice (Edward S. Brodkin).Genes for sex hormone receptors controlling mouse aggression (Donald Pfaff, Elena Choleris and Sonoko Ogawa). General discussion I.Molecular architecture of pheromone sensing in mammals (Catherine Dulac).Serotonergic gene inactivation in mice: models for anxiety and aggression? (Klaus-Peter Lesch).Effects of nitric oxide on the HPA axis and aggression (Randy J.Nelson).General discussion II.Serotonergic mechanisms in aggression (Berend Olivier).Vasopressin/oxytocin and aggression (Craig F. Ferris).Typology of human aggression and its biological control (Manuela Martinez and Concepcion Blasco-Ros).Aggression and social behaviour in rhesus monkeys (Stephen J. Suomi).The role of monoamine oxidase A (MAOA) in the aetiology of antisocial behaviour: the importance of gene environment interactions (Ian W. Craig).Final discussion.Index of contributors.Subject index.

"This is an excellent review of the current state of neurobiological research on aggression…should be essential reading for any scientist working in the field." (Doody's Health Services)