Molecular Dynamics Analyses of Prion Protein Structures

The Resistance to Prion Diseases Down Under

Inbunden, Engelska, 2018

AvJiapu Zhang

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Other PrP models and doppel models are also MD studied in this book. Secondly, all the mutants of mouse PrP and human PrP are well studied by this book.

Produktinformation

Utgivningsdatum2018-08-07
Mått155 x 235 x undefined mm
FormatInbunden
SpråkEngelska
SerieFocus on Structural Biology
Antal sidor375
FörlagSpringer Verlag, Singapore
ISBN9789811088148

Tillhör följande kategorier

Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik

Preface.- Basic Knowledge.- Part I Prion Resistance Species.- Rabbits -Wild-type and Mutants.- Dogs -Wild-type and D159NMutant.- Horses, Buffaloes, and Pigs.- Chicken, Turtles, and Frogs.- Other Species.- Part II b 2-a2 Loop.- Wild-type Mouse 37 oC and 19.85 oC Structures.- Mouse Mutants.- Other Species with an Ordered b 2-a2.- Part III Human Mutants.- Human Mutants.- Human PrPC Monomer, Dimer and Its M129V Mutant.- Human Peptides.- Part IV PrP Binding/Docking.- PrP Bounded to Antibodies, Nanobody, RNA aptamer, etc.- Potential Antiprion Drugs.- Part V Prion Peptides with Cross-b Structures.- Mathematical Formulas for All PrP Peptides’ cross-b structures.- Hydrogen Bonds Between Two Optimized Fundamental Chains of Each Model.- References.