Molecular Diagnostics

W. Edward Highsmith, Jr., PhDMayo Clinic College of Medicine, Department of Laboratory Medicine and Pathology, Molecular Genetics Laboratory, Rochester, MN, USA

• Clinical FISH Testing for the Diagnosis of Solid Tumors.- Epidermal Growth Factor Receptor Testing in Lung Adenocarcinoma.- The Human Epidermal Growth Factor Receptor 2 (HER2).- Tamoxifen and Irinotecan Pharmacogenomics.- Hepatitis C Virus Testing.- Laboratory Testing for HIV Infection: Advances after 27 years.- Detection of Herpes Simplex Virus in Cerebrospinal Fluid using Real-time PCR.- Toward a Safer Blood Supply: The Impact of Molecular Testing.- Chromosomal Microarrays.- BRCA1 and BRCA2 Testing in Inherited Breast Cancer.- Cystic Fibrosis: Carrier Testing, Newborn Screening, and Diagnostic Testing.- Newborn Screening by Tandem Mass Spectrometry and Molecular Confirmation.- Next Generation Clinical Diagnostics: The Sequence of Events.

From the reviews: "This book is intended for molecular pathologists, clinical laboratory directors, genetics/pathology residents/fellows, and clinical laboratory science students. It also would be of great interest to practitioners who use test results from these methodologies in their daily practice -- infectious disease physicians, oncologists, geneticists, neonatologists, obstetricians, etc. -- interested in the technology behind the tests. ... This is the book to read if you want a quick, concise, and relatively current update on molecular diagnostic tests that have truly changed medical practice." (Valerie L. Ng, Doody's Book Reviews, January, 2014)