Molecular Diagnostics and Treatment of Pancreatic Cancer

Asfar Azmi, PhD, is an Assistant Professor at the Department of Oncology, Wayne State University. He has more than a decade of research experience in the area of cancer biology and drug discovery. Dr. Azmi’s lab has made significant pre-clinical discoveries in advanced animal tumor models that helped the clinical development of new cancer drugs. Dr. Azmi has considerable experience in the area of early phase clinical research. Several agents developed by his team have gone into Phase II clinical studies. He has published more than 100 cancer research articles and has edited three additional books, among which there are the Elsevier publications Molecular Diagnostics and Treatment of Pancreatic Cancer as well as Conquering Ras. He is the recipient of numerous young investigator awards from premier scientific bodies. The National Institute of Health and pharmaceutical industry have continuously funded his lab.

• 1. An Integrated Systems Approach to the Study of Pancreatic Cancer2. Systems Biology of Pancreatic Cancer: The Role of Tumor-Microenvironment Communication in Development, Progression and Therapy Resistance3. Proteomics of Pancreatic Cancer Stem Cells4. Systems and Network Guided Pancreatic Cancer Drugs5. Prioritizing Pancreatic Cancer Related miRNAs Using Systems Platform6. Pancreatic Proteome Guided Biomarker Discovery7. Proteomic Analysis of Pancreatic Biopsies8. RNAi Screen in Pancreatic Cancer Drug Development9. Modeling Apoptotic Signaling in Pancreatic Cancer10. Genetic, Epigenetic, and Proteomic Evaluation Post Laser Microdissection of Pancreatic Tumors11. Proteomic Analysis of Gemcitabine Toxicity12. Understanding Pancreatic Cancer through Proteomics of Stellate Cells in Rat Models13. Genome Wide CpG Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas14. Proteomic Profiling of Archival Lesions in Pancreatic Cancer15. Computational Assessment of Benign and Potentially Malignant Pancreatic Cysts16. Pancreatic Cancer Pharmacogenomics17. Systems Biology on Pancreatic Splice Variants18. Systems and Network for Pancreatic Cancer Drug Discovery

"...a well-written book on the use of cutting-edge technology in bioinformatics and computational modeling and how information from these assays can be used to discover new links between system elements in pancreatic cancer. Score: 77 - 3 Stars"--Doodys.com, January 30, 2015"...describes the different emerging applications of systems biology that are shaping modern pancreatic cancer research...provides insights into important network evaluation methodologies related to microRNAs targetome..."--Anticancer Research, January 2015