Molecular Biology

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave. Nanette J. Pazdernik has devoted her career to the understanding of molecular biology and biotechnology, and then disseminating that knowledge by writing and teaching. She is a co-author of Biotechnology, 2nd edition and Molecular Biology, 3rd edition, with Dr. David P. Clark and Dr. Michelle McGehee. Both the second and third edition of Molecular Biology won a Texty award from the Textbook and Academic Authors Association. She has taught courses in General Biology, Genetics, as well as Anatomy and Physiology at Southwestern Illinois College, McKendree University, and Harris-Stowe University. She received her BA in Biology from Lawrence University in Appleton, Wisconsin, and her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota. Her doctoral thesis studied protein structure-function relationships. Following her degrees, she investigated the signal transduction pathways that control apoptosis and immunity at Indiana University School of Medicine. In a second post-doctoral position, she studied the various molecules that maintain the stem cell niche in the Department of Genetics at Washington University School of Medicine in St. Louis, MO. Currently, Dr. Pazdernik works in the biotech industry as a scientific writer.Michelle R. McGehee earned a BA in Microbiology in 2000 and a PhD in Molecular Biology, Microbiology, and Biochemistry in 2005, both from Southern Illinois University in Carbondale, USA. Her graduate research focused on the genetic and biochemical regulation of lactate fermentation in Escherichia coli. Michelle is currently an assistant academic dean and biology professor at a college in Texas, where she teaches courses in both microbiology and genetics.

• Unit 1: Basic Chemical and Biological Principles1. Cells and Organisms2. Basic Genetics3. DNA, RNA, and Protein4. Genes, Genomes, and DNA5. Manipulation of Nucleic AcidsUnit 2: The Genome6. The Polymerase Chain Reaction7. Cloning Genes for Analysis8. DNA Sequencing9. Genomics and Systems BiologyNew Chapter to cover metagenomics, symbiosis, epigenomics etcUnit 3: The Central Dogma of Molecular Biology10. Cell Division and DNA Replication11. Transcription of Genes12. Processing of RNA (moved to Unit 4)13. Protein Synthesis14. Protein Structure and Function15. Proteomics: Global Analysis of ProteinsUnit 4: Regulating Gene Expression16. Regulation of Transcription in Prokaryotes17. Regulation of Transcription in Eukaryotes12. Processing of RNA (moved from Unit 3)18. Regulation at the RNA LevelNew Chapter on Genome defense (RNAi and CRISPR). Would include their use in genetic analysis and genome editing19. Analysis of Gene Expression (Transcriptome)Unit 5: Subcellular Life Forms20. Plasmids21. Viruses22. Mobile DNAUnit 6: Changing the DNA Blueprint23. Mutations and Repair24. Recombination25. Bacterial Genetics26. Molecular Evolution

Select Guide Rating