Molecular Biology of Neurodegenerative Diseases

David B. Teplow, Ph.D., is a Professor of Neurology, Emeritus, at UCLA and an internationally recognized leader in efforts to understand and treat Alzheimer's disease. Dr. Teplow's group has used a multi-disciplinary approach to determine how neurotoxic peptides, such as the amyloid β-protein (Alzheimer's disease) and α-synuclein (Parkinson’s disease), form neurotoxic structures that kill neurons and to develop the means to block these processes. Dr. Teplow received undergraduate training at UC Berkeley; a Ph.D. from the University of Washington; and was a postdoctoral scholar at Caltech. Before coming to UCLA, Dr. Teplow was a faculty member in the Department of Neurology, Harvard Medical School. Dr. Teplow has published >250 peer-reviewed articles, books and book chapters, and commentaries, in addition to serving on numerous national and international scientific advisory boards. Dr. Teplow was a founding editor of the Journal of Molecular Neuroscience and Current Chemical Biology, He is Editor-in-Chief of the Elsevier serial Progress in Molecular Biology and Translational Science and is Associate Editor-in-Chief of the American Journal of Neurodegenerative Disease.

• Neuropathology and imaging Harry Vinters Neuropathology and imaging Thompson, Paul Age-dependence of neurodegenerative diseases (organismal genetics) Tanzi, Rudolph AD Dominic Walsh PD Guo, Ming PD Rochet, Chris and Prion I: Human Surewicz, Witold Prion II: Yeast Tuite, Mick Cerebral amyloid angiopathy Cerebral amyloid angiopathy Yamada, Masahito Naiki, Hironobu Tau, and Gloria Lee Membrane Pores Kagan, Bruce Unfolded protein response ALS Dokholyan, Nikolay CAG-repeat diseases Chris Ross Mitochondria Lee Martin

Praise for the series: "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal