Molecular and Cellular Mechanisms of Antibody Activity

Inbunden, Engelska, 2013

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Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. This book examines how these new results have dramatically changed our view of how antibodies function in vivo.

Produktinformation

Utgivningsdatum2013-05-22
Mått155 x 235 x 22 mm
Vikt592 g
FormatInbunden
SpråkEngelska
Antal sidor294
Upplaga2013
FörlagSpringer-Verlag New York Inc.
ISBN9781461471066

Tillhör följande kategorier

Onkologi inom Medicin
Patologi inom Medicin

IgM and IgD in infection and inflammatory diseases.- Immunoglobulin A – molecular mechanisms of function and role in immune defense.- Crystal structures of human IgG Fc-fragments and their complexes with Fc Receptors.- The role of IgG in immune responses.- Molecular and cellular pathways involved in the anti-inflammatory activity of IgG.- Example of the Pathogenic Potential of Two Sets of Autoantibodies: Anti-RBC and IgG3 RF Cryoglobulins.- Cross-talk between antibodies, IgG Fc receptors and the complement system.- Regulation of immunological responses by the neonatal Fc receptor for IgG, FcRn.- Antibody mediated regulation of humoral immunity.- Engineered antibody derivatives in preclinical and clinical development.