Molecular and Cell Biology of Cancer

Professor Dr. Rita Fior teaches Molecular and Cell Biology of Cancer at the Faculty of Sciences in the University of Lisbon, Portugal. She is also a Principal Investigator at the Champalimaud Foundation, a renowned state-of-the-art center for Science. She has worked with Julian Lewis (Emeritus Scientist and Fellow of the Royal Society, CRUK). Professor Dr. Rita Zilhão has been teaching for more than 20 years at the Faculty of Sciences in the University of Lisbon, Portugal. At this moment she is responsible for 3 courses: Genetic and Molecular Biology, Basics of Molecular Biology and Molecular and Cell Biology of Cancer. She is the coordinator of the Molecular and Genetic Biology Bachelor Program.

• Preface.- Molecular and Cell Biology of Cancer when cells break the rules and hijack their own planet.- Cancer as an Evolutionary Process.- Cell signaling in cancer.- The cell cycle, cytoskeleton and cancer.- Genomic Instability: DNA Repair and Cancer.- Cell metabolism in cancer – an energetic switch.- Cancer immunoediting and hijacking of the immune system.- Angiogenesis - vessels recruitment by tumor cells.- Tumor niche disruption and metastasis: the role of epithelial-mesenchymal transition (EMT).- Case studies - Molecular Pathology perspective and impact on oncologic patients’ management.- Index.