Annetine C. Gelijns, Editor; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 Front Matter; 2 1. Medical Technology Development: An Introduction to the Innovation-Evaluation Nexus; 3 2. The Selection of Endpoints in Evaluation Research; 4 3. Advances in Health Status Measurement: The Potential to Improve Experimental and Non-Experimental Data Collection; 5 4. What is Outcomes Research?; 6 5. Strengths and Weaknesses of Health Insurance Data Systems for Assessing Outcomes; 7 6. Perscription-Event Monitoring: An Example of Total Population Post-Marketing Drug Serveillance; 8 7. The Role of Decision Analysis in the Translation of Research Findings into Clinical Practice; 9 8. Meta-Analysis: A Quantitative Approach to Research Integration; 10 9. An Introduction to a Bayesian Method for Meta-Analysis: The Confidence Profile Method; 11 10. Should We Change the Rules for Evaluating Medical Technologies?; 12 11. Attitudinal Factors That Influence the Utilization of Modern Evaluative Methods; 13 Appendix A: Comparing the Development of Drugs, Devices, and Clinical Procedures; 14 Appendix B: Workshop Agenda; 15 Appendix C: Contributors; 16 Index

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Annetine C. Gelijns, Editor; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 Front Matter; 2 1. Medical Technology Development: An Introduction to the Innovation-Evaluation Nexus; 3 2. The Selection of Endpoints in Evaluation Research; 4 3. Advances in Health Status Measurement: The Potential to Improve Experimental and Non-Experimental Data Collection; 5 4. What is Outcomes Research?; 6 5. Strengths and Weaknesses of Health Insurance Data Systems for Assessing Outcomes; 7 6. Perscription-Event Monitoring: An Example of Total Population Post-Marketing Drug Serveillance; 8 7. The Role of Decision Analysis in the Translation of Research Findings into Clinical Practice; 9 8. Meta-Analysis: A Quantitative Approach to Research Integration; 10 9. An Introduction to a Bayesian Method for Meta-Analysis: The Confidence Profile Method; 11 10. Should We Change the Rules for Evaluating Medical Technologies?; 12 11. Attitudinal Factors That Influence the Utilization of Modern Evaluative Methods; 13 Appendix A: Comparing the Development of Drugs, Devices, and Clinical Procedures; 14 Appendix B: Workshop Agenda; 15 Appendix C: Contributors; 16 Index

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Annetine C. Gelijns, Editor; Committee on Technological Innovation in Medicine, Institute of Medicine

• 1 Front Matter; 2 1. Medical Technology Development: An Introduction to the Innovation-Evaluation Nexus; 3 2. The Selection of Endpoints in Evaluation Research; 4 3. Advances in Health Status Measurement: The Potential to Improve Experimental and Non-Experimental Data Collection; 5 4. What is Outcomes Research?; 6 5. Strengths and Weaknesses of Health Insurance Data Systems for Assessing Outcomes; 7 6. Perscription-Event Monitoring: An Example of Total Population Post-Marketing Drug Serveillance; 8 7. The Role of Decision Analysis in the Translation of Research Findings into Clinical Practice; 9 8. Meta-Analysis: A Quantitative Approach to Research Integration; 10 9. An Introduction to a Bayesian Method for Meta-Analysis: The Confidence Profile Method; 11 10. Should We Change the Rules for Evaluating Medical Technologies?; 12 11. Attitudinal Factors That Influence the Utilization of Modern Evaluative Methods; 13 Appendix A: Comparing the Development of Drugs, Devices, and Clinical Procedures; 14 Appendix B: Workshop Agenda; 15 Appendix C: Contributors; 16 Index

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