Tarun Jha is the senior most Professor of the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has already supervised 20 Ph.D. students and is guiding 4 more for that. He also guided 6 post-doctoral fellows and completed 9 research projects. He has published 200 research articles and 10 book chapters as well as jointly edited a book. Prof. Jha is one of the Editorial Board Members of the journal ‘SAR and QSAR in Environmental Research’ published by Taylor and Francis. He is also serving as a reviewer of 26 internationally reputed journals. His research area includes the design, synthesis, and biological evaluation of anticancer small molecules, especially inhibitors of zinc-dependent metalloenzymes.

• Part A: Fundamentals of molecular modelingChapter 1 2D-QSAR studies: Regression and classification-based QSAR studiesChapter 2 3D-QSAR studies: CoMFA, CoMSIA and Topomer CoMFA methodsChapter 3 Other modeling approaches: Pharmacophore mapping, molecular docking and molecular dynamic simulation studiesPart B: Matrix metalloporteinases and their inhibitorsChapter 4 Collagenases and their inhibitorsChapter 5 Gelatinases and their inhibitorsChapter 6 Stromelysins and their inhibitorsChapter 7 Matrilysins and their inhibitorsChapter 8 Membrane-type MMPs and their inhibitorsChapter 9 Other MMPs and their inhibitorsPart C: Modeling of MMP inhibitorsChapter 10 Modeling inhibitors of CollagenasesChapter 11 Modeling inhibitors of GelatinasesChapter 12Modeling inhibitors of StromelysinsChapter 13 Modeling inhibitors of MatrilysinsChapter 14 Modeling inhibitors of membrane-type MMPsChapter 15 Modeling inhibitors of other MMPsPart D: Conclusion and Future PerspectiveChapter 16Conclusion and Future Perspectives

Tarun Jha is the senior most Professor of the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has already supervised 20 Ph.D. students and is guiding 4 more for that. He also guided 6 post-doctoral fellows and completed 9 research projects. He has published 200 research articles and 10 book chapters as well as jointly edited a book. Prof. Jha is one of the Editorial Board Members of the journal ‘SAR and QSAR in Environmental Research’ published by Taylor and Francis. He is also serving as a reviewer of 26 internationally reputed journals. His research area includes the design, synthesis, and biological evaluation of anticancer small molecules, especially inhibitors of zinc-dependent metalloenzymes.

• Part A: Fundamentals of molecular modelingChapter 1 2D-QSAR studies: Regression and classification-based QSAR studiesChapter 2 3D-QSAR studies: CoMFA, CoMSIA and Topomer CoMFA methodsChapter 3 Other modeling approaches: Pharmacophore mapping, molecular docking and molecular dynamic simulation studiesPart B: Matrix metalloporteinases and their inhibitorsChapter 4 Collagenases and their inhibitorsChapter 5 Gelatinases and their inhibitorsChapter 6 Stromelysins and their inhibitorsChapter 7 Matrilysins and their inhibitorsChapter 8 Membrane-type MMPs and their inhibitorsChapter 9 Other MMPs and their inhibitorsPart C: Modeling of MMP inhibitorsChapter 10 Modeling inhibitors of CollagenasesChapter 11 Modeling inhibitors of GelatinasesChapter 12Modeling inhibitors of StromelysinsChapter 13 Modeling inhibitors of MatrilysinsChapter 14 Modeling inhibitors of membrane-type MMPsChapter 15 Modeling inhibitors of other MMPsPart D: Conclusion and Future PerspectiveChapter 16Conclusion and Future Perspectives

Tarun Jha is the senior most Professor of the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has already supervised 20 Ph.D. students and is guiding 4 more for that. He also guided 6 post-doctoral fellows and completed 9 research projects. He has published 200 research articles and 10 book chapters as well as jointly edited a book. Prof. Jha is one of the Editorial Board Members of the journal ‘SAR and QSAR in Environmental Research’ published by Taylor and Francis. He is also serving as a reviewer of 26 internationally reputed journals. His research area includes the design, synthesis, and biological evaluation of anticancer small molecules, especially inhibitors of zinc-dependent metalloenzymes.

• Part A: Fundamentals of molecular modelingChapter 1 2D-QSAR studies: Regression and classification-based QSAR studiesChapter 2 3D-QSAR studies: CoMFA, CoMSIA and Topomer CoMFA methodsChapter 3 Other modeling approaches: Pharmacophore mapping, molecular docking and molecular dynamic simulation studiesPart B: Matrix metalloporteinases and their inhibitorsChapter 4 Collagenases and their inhibitorsChapter 5 Gelatinases and their inhibitorsChapter 6 Stromelysins and their inhibitorsChapter 7 Matrilysins and their inhibitorsChapter 8 Membrane-type MMPs and their inhibitorsChapter 9 Other MMPs and their inhibitorsPart C: Modeling of MMP inhibitorsChapter 10 Modeling inhibitors of CollagenasesChapter 11 Modeling inhibitors of GelatinasesChapter 12Modeling inhibitors of StromelysinsChapter 13 Modeling inhibitors of MatrilysinsChapter 14 Modeling inhibitors of membrane-type MMPsChapter 15 Modeling inhibitors of other MMPsPart D: Conclusion and Future PerspectiveChapter 16Conclusion and Future Perspectives