Microscopy, Optical Spectroscopy, and Macroscopic Techniques

• Microscopy.- Electron Microscopy of Protein-Nucleic Acid Complexes.- Visualization of Unshadowed DNA by Electron Microscopy.- Biological Applications of Scanning Tunneling Microscopy.- Scattering And SedimentatioN.- High-Flux X-Ray and Neutron Solution Scattering.- Determination of Macromolecular Homogeneity, Shape, and Interactions Using Sedimentation Velocity Analytical Ultracentrifugation.- Determination of Absolute Molecular Weights Using Sedimentation Equilibrium Analytical Ultracentrifugation.- Classical Light Scattering for the Determination of Absolute Molecular Weights and Gross Conformation of Biological Macromolecules.- Determination of Diffusion Coefficients of Biological Macromolecules by Dynamic Light Scattering.- Calorimetric Methods.- to Microcalorimetry and Biomolecular Energetics.- Differential Scanning Calorimetry.- Isothermal Titration Microcalorimetry.- Optical Spectroscopy.- Optical Spectroscopy.- The Measurement of Electronic Absorption Spectra in the Ultraviolet and Visible.- Analysis of Polypeptide and Protein Structures Using Fourier Transform Infrared Spectroscopy.- Fluorescence Spectroscopy.- Circular Dichroism.

...a quite fascinating book. It describes a range of techniques with which I am familiar in the literature, but have never actually used and explains the practicalities behind the instrumentation and its use...very readable and informative.-Dave Roberts, Natural History Museum-Society for General Microbiology Quarterly