MicroRNA Cancer Regulation

Advanced Concepts, Bioinformatics and Systems Biology Tools

Häftad, Engelska, 2016

Av Ulf Schmitz, Olaf Wolkenhauer, Julio Vera

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This edited reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. Bioinformaticians and modellers are provided with a general perspective on microRNA biology in cancer, and the state-of-the-art in computational microRNA biology.

Produktinformation

Utgivningsdatum2016-08-23
Mått178 x 254 x 20 mm
Vikt677 g
FormatHäftad
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor346
FörlagSpringer
ISBN9789402400793

Tillhör följande kategorier

Onkologi inom Medicin
Biovetenskap inom Naturvetenskap och teknik
Medicinsk utrustning och medicinska tekniker inom Medicin

Preface.- 1 MicroRNAs in human cancer.- 2 Bioinformatics, non-coding RNAs and its possible application in personalized medicine .- 3 MicroRNA target prediction and validation.- 4 MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology.- 5 The p53/microRNA network in cancer: experimental and bioinformatics approaches.-6 MicroRNAs in melanoma biology.- 7 MicroRNA in the lung.- 8 The E2F1-miRNA cancer progression network.- 9 Modeling of microRNA-transcription factor networks in cancer.- 10 Coordinated networks of microRNAs and transcription factors with evolutionary perspectives.- 11 Mathematical modeling of microRNA-mediated mechanisms of translation repression.- 12 Web resources for microRNA research.- 13 Discovery of microRNA regulatory networks by integrating multidimensional high-throughput data.- 14 Discovering the functional microRNA-mRNA regulatory modules in heterogeneous data.- 15 Elucidating the role of microRNAs in cancer through data mining techniques.- 16 Working together: Combinatorial regulation by microRNAs.