Microbiota-Gut-Brain Axis and CNS Disorders

Recent Progress and Perspectives

Häftad, Engelska, 2025

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Microbiota-Gut-Brain Axis and CNS Disorders: Recent Progress and Perspectives on Human Disease summarizes the main findings on gut-brain axis in different types of CNS disorders, providing a complete overview of the field. The content helps unravel the complex interactions of the microbiota-gut-brain-axis in CNS disorders to pave a better understanding of microbiota-mediated pathogenesis, avenues for noninvasive prognosis, and therapeutic possibilities leveraging microbiota-gut-brain-axis modulations. Coverage includes the role of the microbiota-gut-brain axis and gut virome on human diseases including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease, Depression and Anxiety, Autism Spectrum Disorder, Multiple Sclerosis, Stroke, and others.

This book will satisfy the urgent need for a broader view of the current associations between gut microbiota alterations and development of CNS disorders, including the use of novel therapeutic approaches for restoring the correct intestinal bacteria content. It is the perfect reference for translational and clinical gut and microbiome researchers tackling the challenges of delivering genes and drugs in a more targeted and efficient manner for the treatment of CNS disorders.

Discusses the development of both health and disease in interdisciplinary research involving gut microbiology
Provides an understanding the role of Microbiome-Gut-Brain axis in neurodegenerative and neurodevelopmental diseases, including central nervous system (CNS) malignancies
Delivers a compilation of current clinical studies to further investigate the role of diet in varying neurological disorders

Produktinformation

Utgivningsdatum2025-01-29
Mått191 x 235 x 24 mm
Vikt1 050 g
FormatHäftad
SpråkEngelska
Antal sidor514
FörlagElsevier Science
ISBN9780443216800

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Dr. Neeraj Mishra is a Professor at the Amity Institute of Pharmacy, Gwalior, where he has served since July 2019. He has over 20 years of teaching and research experience and more than 150 international and national publications in novel, localized, targeted, and controlled drug delivery systems, including nano- and microparticles for the treatment of breast and colon cancer and neurodegenerative disorders. Dr. Mishra has authored 25 books and 45 book chapters with leading publishers such as Elsevier, Bentham, Springer, and Wiley, and holds five patents (three international and two Indian). His honors include the Distinguished Professor Awards (2019, 2021), Outstanding Scientist Award (2020), and Best Academician Award (2023). In 2025, he was recognized as one of the World’s Top 2% Scientists by Stanford University and Elsevier. Dr. Anoop Kumar is an Assistant Professor in the Department of Pharmacology at Delhi Pharmaceutical Sciences & Research University (DPSRU), India. With a distinguished career, he has previously served as an Assistant Professor and Head at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, and as Head and Associate Professor at ISF College of Pharmacy, Moga, Punjab. Dr. Kumar has also held research positions at Sun Pharmaceutical Industries Limited and Translational Health Science Institute (THSTI). He earned his Ph.D. from Birla Institute of Technology, Mesra, Ranchi, as a DST INSPIRE Fellow. He is an Associate Editor for Health Sciences Review and Acta Neurologica Scandinavica. His research focuses on drug repurposing, clinical trial meta-analysis, pharmacoeconomics, and pharmacovigilance.

1. Introduction: An overview of Microbiota-Gut- Brain Axis2. Role of Microbiota-Gut- Brain Axis in Alzheimer disease and possible interventions3. Role of Microbiota Gut- Brain axis in Parkinson’s disease4. Role of Microbiota-Gut- Brain Axis in Huntington’s disease and possible interventions5. Role of Microbiota-Gut- Brain Axis in depression and anxiety6. Role of microbiome- Gut Brain axis in autism spectrum disorder (ASD)7. Role of Microbiota- Gut brain axis in autoimmunity and Multiple Sclerosis8. Role of Microbiome Gut- Brain axis in stress9. Role of Microbiota- Gut Brain Axis in epilepsy and possible interventions10. Role of Microbiota- Gut Brain Axis in migraine and possible interventions11. Role of Microbiota- Gut Brain Axis in stroke and possible interventions12. Role of Microbiota- Gut Brain Axis in brain infections and possible interventions13. Role of Microbiome Gut- Brain axis in brain disorders14. Role of GUT microbiota in neuropsychiatric and neurological disorders15. Role of Microbiota- Gut Brain Axis in Obesity on Cognitive Functions and Mood16. Role of Microbiota- Gut Brain Axis on Neurotransmitters modulation17. Role of gut virome and mycobiome in neurological disorders18. Role of nutraceuticals in neurological diseases19. Future prospective of Microbiome- Gut brain axis for treatment of CNS disorders