Metabolic Syndrome

Dr Mukhopadhyay has been involved in patient care, teaching and research for more than two decades. In addition to teaching MD students for their postdoc (DM) degree in Endocrinology & Metabolic disorders, he also guides research fellows and postdocs for their translational work involving metabolic syndrome (MetS). He has been working on the role of the hepatokine fetuin-A on metabolic syndrome. He is also working on a peroxyvanadate compound that prevents the progression of MetS to T2DM by inhibiting Fetuin-A. His group was credited with the first randomized controlled trial (RCT) on the impact of vitamin D treatment on IR and progression of people with MetS to T2D, discodering a role of vitamin D in the prevention of progression of MetS. Dr. Sunetra Mondal obtained her Doctorate of Medicine degree in the subject of Endocrinology and Metabolism in the year 2019 and MD in Medicine in the year 2016. She is currently a postdoctoral senior resident in the Dept of Endocrinology, Institute of Postgraduate Medical Education & Research and has been working on the largest cohort of Turner Syndrome in India, doing research on their genetics and phenotypic aspects including their metabolic parameters and body composition parameters.

• Section 1: Introduction to Metabolic Syndrome1. Beyond the Metabolic Syndrome: Adverse Lifelong Influences Emanating From Insulin Resistance On The Aging Process In Non-Diabetics2. Metabolic syndrome- is it a disease or a risk factor for other disorders?3. Intrauterine malnutrition and future risk of Metabolic Syndrome4. Intervening at the stage of metabolic syndrome to prevent type 2 diabetes- is it justified?5. Dietary fats and Metabolic Syndrome: How strong is the association?6. Metabolic Syndrome needs treatment but with lifestyle interventions aloneSection 2: Epidemiology of Metabolic Syndrome7. Epidemiology of Metabolic Syndrome: Global Scenario8. Epidemiology of Metabolic Syndrome in South and South East Asians9. Barker's Hypothesis and Metabolic Syndrome10. Metabolic syndrome in Australian aboriginesSection 3: Pathogenesis and pathophysiology of Metabolic Syndrome11. Diet in the pathogenesis of metabolic syndrome: Role of Sugar, salt and fat12. Vitamin D deficiency and metabolic syndrome – Is there a causality?13. Role of inflammation in the pathogenesis of Metabolic Syndrome14. Role of oxidative stress in the pathogenesis of Metabolic Syndrome15. Mitochondrial dysfunction and Metabolic syndrome16. The entero-insular axis and metabolic syndrome17. Type I interferons in metabolic syndrome18. Immunometabolism, an emerging subspecialty of Metabolic Syndrome19. Pathophysiology of metabolic syndrome: current concepts20. Role of Circadian rhythms in Metabolic Syndrome21. Ectopic fat distribution and its role in Metabolic Syndrome22. The role of genetic and epigenetic factors in familial clustering of metabolic syndrome23. High carbohydrate diet in the pathogenesis of Metabolic Syndrome24. Endocrine disruptors in the pathogenesis of metabolic syndrome25. Autoimmunity and Metabolic SyndromeSection 4: Metabolic Syndrome – multisystemic manifestation26. The burden of atherosclerotic cardiovascular disease in metabolic syndrome27. Mechanisms of atherosclerosis in metabolic syndrome28. NAFLD, the hepatic manifestation of metabolic syndrome29. Obesity associated hypogonadism - a growing concern in metabolic syndrome30. Sleep apnea – A cause or a consequence of Metabolic Syndrome?31. The metabolic syndrome in psychiatry32. Renal manifestations of Metabolic Syndrome: The link between obesity and chronic kidney disease33. Unraveling neuropathic manifestations of metabolic syndrome: role of corneal confocal microscopy34. Metabolic Syndrome and Periodontitis: pathophysiologic links and clinical implications35. Metabolic Syndrome and Bone Health36. Insulin resistance and the risk of Osteoporosis37. Glucagon and Metabolic SyndromeSection 5: Clinical assessment of Metabolic Syndrome38. Measures of adiposity– from BMI to Waist circumference to neck circumference to body fat39. The Role of Prediabetes in the Metabolic Syndrome40. Assessment of insulin resistance: from the bench to bedsideSection 6: Management of Metabolic Syndrome41. Dietary interventions to combat obesity and Metabolic Syndrome42. Role of precision diet and intermittent fasting in the management of metabolic syndrome43. Nutritional and Cognitive interventions to reduce cardiovascular risk in Metabolc Syndrome44. Role of exercise in the prevention and management of Metabolic Syndrome45. Should Vitamin D be used to treat Metabolic Syndrome?46. Pharmacologic therapies in Metabolic syndrome with special reference to NAFLD47. Role of newer anti-diabetes drugs in prediabetes: A systematic review48. Management of Insulin resistance in PCOS49. The role of bariatric surgery in the management of metabolic syndrome50. Anti-inflammatory interventions to mitigate cardiovascular risk in metabolic syndrome51. Management of new onset dysglycemia in transplant recipients52. Prevention of Type 2 diabetes in Metabolic Syndrome: Role of the geneticist53. Managing Metabolic Syndrome in a general practice setting54. Dietary interventions to reduce cardiovascular risk in Metabolic Syndrome55. Management of Lipid Abnormalities in Metabolic SyndromeSection 7: Metabolic Syndrome in children and adolescents56. Overview of metabolic syndrome in children and adolescents57. Overview of metabolic syndrome in children and adolescents: Indian perspective58. Metabolic syndrome in children and adolescents: Does ethnicity matter?59. NAFLD in children and adolescents60. PCOS in adolescents: Role of insulin resistance61. The inter relationship between polycystic ovary syndrome (PCOS) and metabolic syndrome62. Dietary interventions to improve cardiometabolic health outcomes in children and adolescentsSection 8: Metabolic Syndrome: Controversies to consensus63. Metabolic Syndrome -are our definitiond fit for purpose?64. Metabolic Syndrome: treat the whole or address each part?65. Metabolic Syndrome and cancer riskSection 9: Areas for future research66. Assessment of abdominal obesity: to measure visceral fat, subcutaneous fat or both?67. Obesity-mediated insulin resistance in target tissues: Role of adipokines, hepatokines and myokines68. Can bariatric surgery cure metabolic syndrome?69. Gut microbiota and metabolic syndrome: what’s new?70. COVID19 and metabolic syndrome – an unholy alliance71. MicroRNA modulation in metabolic syndrome: a novel insight in cardiometabolic disease72. Role of artificial intelligence in tackling the metabolic syndrome pandemic73. Glucose handling by the brain and its impact on metabolic syndrome74. Impact of Hypoglycemia on cardiovascular risk in metabolic syndrome75. Dietary interventions to combat obesity in metabolic syndrome- role of time restricted eating

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