Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics

Dr. Naresh Kasoju is a Scientist at Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala. He obtained his Ph.D. in Biotechnology from Indian Institute of Technology and postdoctoral experience from Institute of Macromolecular Chemistry, Prague, Czech Republic and University of Oxford, Oxford, UK. His research interests include mesenchymal stem cells-based therapeutics for regenerative medicine, natural polymers-based biomaterials for biomedical applications, and 3D bioprinting based approaches for tissue engineering. He filed 06 Indian patents and 03 Indian design registrations and has published 70+ articles, with 4500+ citations. He's editor of 3 books, guest editor for 3 special issues, editorial board member for 2 journals and reviewer for 50+ journals. He's a member of National Academy of Science, India and Royal Society of Biology, UK. Recently, he received Young Scientist Award by Indian Academy of Biomedical Sciences, Lucknow for his outstanding contributions in biomaterials, stem cells and tissue engineering. Dr. Ramesh Bhonde joined Dr D Y Patil University, Pune, as Director (Research) in September 2016. Prior to that he served as Professor & Dean, at the School of Regenerative Medicine, Bangalore for the last 5 years. He retired from National Center for Cell Science Pune as Scientist ‘F’ and joined Stempeutics Research Pvt. Ltd. Bangalore as Technical Director, moving to Stempeutics Research Malaysia branch in Kuala Lumpur, Malaysia. He’s worked in the field of pancreatic regeneration in diabetes for the past 25 years. His areas of interest and expertise include stem cells, regenerative biology, tissue banking and engineering, with special reference to the cultivation of fastidious cells such as hepatocytes, vascular endothelial cells, and islets of Langerhans. He’s well trained in hESC and iPS technology. Dr. Bhonde authored 7 book chapters, and is a recipient of Dr. TMA Pai Endowment Chair in Islet Engineering & Banking in October 2013.

• Section 1: Basic and emerging concepts1. Introduction to stem cell biology2. Introduction to extracellular vesicles biology3. An overview on mesenchymal stem cells in regenerative medicine4. An overview on extracellular vesicles in regenerative medicine5. Engineering stem cells for enhanced organ retention, biodistribution and targeted delivery6. Engineering extracellular vesicles for enhanced organ retention, biodistribution and targeted delivery7. Challenges and advances in biomanufacturing of mesenchymal stem cells: from isolation, scale-up, storage, transportation to bench side application8. Challenges and advances in biomanufacturing of extracellular vesicles: from isolation, scale-up, storage, transportation to bench side application9. Ethical, quality and regulatory considerations in mesenchymal stem cell and extracellular vesicles based therapiesSection 2: Therapeutic applications and disease focus10. Mesenchymal stem cells and extracellular vesicles in skin regeneration11. Mesenchymal stem cells and extracellular vesicles in neural regeneration12. Mesenchymal stem cells and extracellular vesicles in cardiac regeneration13. Mesenchymal stem cells and extracellular vesicles in ocular regeneration14. Mesenchymal stem cells and extracellular vesicles in bone regeneration15. Mesenchymal stem cells and extracellular vesicles in cartilage regeneration16. Mesenchymal stem cells and extracellular vesicles in liver regeneration17. Mesenchymal stem cells and extracellular vesicles in pancreatic regeneration18. Mesenchymal stem cells and extracellular vesicles in lung regeneration19. Mesenchymal stem cells and extracellular vesicles in cancer immunotherapySection 3: Cross-disciplinary innovations and future directions20. Biomaterials in mesenchymal stem cells and extracellular vesicles research21. Bioreactors in mesenchymal stem cells and extracellular vesicles research22. Nanotechnology in mesenchymal stem cells and extracellular vesicles research23. Microfluidics in mesenchymal stem cells and extracellular vesicles research24. AI and ML in mesenchymal stem cells and extracellular vesicles research25. Sustainability approaches in mesenchymal stem cells and extracellular vesicles research26. Systems biology approaches in mesenchymal stem cells and extracellular vesicles research27. Synthetic biology approaches in mesenchymal stem cells and extracellular vesicles research28. Quantum biology approaches in mesenchymal stem cells and extracellular vesicles research29. Mesenchymal stem cells and extracellular vesicles in space medicine: challenges and opportunities