Medical Microbiology and Infection at a Glance

Stephen H. Gillespie is Professor of Medicine in the School of Medicine, University of St. Andrews, Fife, UK. Kathleen B. Bamford is a Consultant Medical Microbiologist at The Royal Cornwall Hospital, Cornwall, UK.

• Biographies viiPreface to the Fifth Edition ixAbout the Companion Website xiPart 1 Concepts 11 Microbial pathogens, classification and concepts 22 Innate and acquired immunity 43 The ‘normal’ flora in health and disease 64 Pathogenicity and pathogenesis of infectious disease 85 Making a microbiological diagnosis of infection 106 Antimicrobial therapy – principals and concepts 127 Antibacterial agents – pharmacology and modes of action 148 Antimicrobial use and stewardship 169 Emergence and detection of resistance 1810 Sources and transmission of infection 2011 Principles of infection control 2212 Infection in the healthcare environment 2413 Immunization 2614 Emerging infections 2815 High consequence infectious diseases and bioterrorism preparedness 30Part 2 Bacteriology 3316 Staphylococcus 3417 Haemolytic streptococcal infections 3618 Other Gram- positive cocci and the alpha- haemolytic streptococci 3819 Streptococcus pneumoniae 4020 Listeria, bacillus, non‐diphtheria corynebacterium 4221 Diphtheria, tetanus and pertussis 4422 Mycobacterium tuberculosis 4623 Non- tuberculous mycobacteria and leprosy 4824 Clostridium 5025 Non- sporing anaerobic infections 5226 Neisseria and Moraxella 5427 Small Gram- negative coccobacilli: Haemophilus, Brucella, Francisella, Yersinia and Bartonella 5628 Pathogenicity of enteric Gram‐negative bacteria 5829 Enterobacteriaceae clinical syndromes 6030 Vibrio, Campylobacter and Helicobacter 6231 Environmental pathogens: Pseudomonas, Burkholderia, Legionella and Acinetobacter 6432 Chlamydia, Mycoplasma and Rickettsia 6633 Spiral bacteria 68Part 3 Virology 7134 Virus structure and classification 7235 Antiviral therapy 7436 Herpesviruses I 7637 Herpesviruses II 7838 DNA viruses: adenovirus, parvovirus and poxvirus 8039 Measles, mumps and rubella 8240 Influenza viruses 8441 Parainfluenza and other respiratory viruses 8642 Enterovirus and viruses that infect the gastrointestinal tract 8843 Hepatitis viruses 9044 Tropical, exotic or arbovirus infections 92Part 4 Mycology 9545 Yeast infections 9646 Filamentous fungi 9847 Antifungal drugs and antifungal therapy 100Part 5 Parasitology 10348 Intestinal protozoa 10449 Malaria, leishmaniasis and trypanosomiasis 10650 Intestinal helminths 10851 Tissue helminths 110Part 6 Systemic infection 11352 Congenital and perinatal infections 11453 HIV infection and AIDS 11654 Pyrexia of unknown origin and puerperal sepsis 11855 Sepsis 12056 Endocarditis, myocarditis and pericarditis 12257 Infections of the central nervous system 12458 Acute respiratory tract infections 12659 Chronic infections of the lung and hospital acquired pneumonia 12860 Urinary and genital infections 13061 Infections of the bones and joints 13262 Bacterial diarrhoeal disease 13463 Zoonoses 13664 Infections in immunocompromised patients 13865 Ocular infections 14066 Infections of the skin and soft tissue 142Index 144