Haruhisa Inoue, CiRA, Kyoto University, Japan; RIKEN BRC, Japan; RIKEN AIP, JAPANYukio Nakamura, RIKEN BioResource Center, Japan

• Introduction. Overview.- Disease Modeling. iPSCs for disease modeling.- Reprogramming cancer cells.- Recapitulating hematopoiesis in the lab.- Modeling cardiomyopathies with iPSCs.- Molecular Technologies. Controling cell state with intracellular biomarkers.- Genome editing of stem cells.- iPS Applications. iPSC-based cell therapy for eye diseases.- 3D models for organ development.- Drug discovery using iPSCs.- Direct differentiation of neural cells.

“The book is most appropriate for those with a basic understanding of molecular biology and stem cell function, with value for students, researchers, and instructors interested in the area of iPS cell biology. … it serves as an excellent resource for those studying this topic and provides a chronological perspective, appropriately discussing many of the key applications and challenges.” (Thomas Bodenstine, Doody's Book Reviews, June 21, 2019)

Haruhisa Inoue, CiRA, Kyoto University, Japan; RIKEN BRC, Japan; RIKEN AIP, JAPANYukio Nakamura, RIKEN BioResource Center, Japan

• Introduction. Overview.- Disease Modeling. iPSCs for disease modeling.- Reprogramming cancer cells.- Recapitulating hematopoiesis in the lab.- Modeling cardiomyopathies with iPSCs.- Molecular Technologies. Controling cell state with intracellular biomarkers.- Genome editing of stem cells.- iPS Applications. iPSC-based cell therapy for eye diseases.- 3D models for organ development.- Drug discovery using iPSCs.- Direct differentiation of neural cells.

“The book is most appropriate for those with a basic understanding of molecular biology and stem cell function, with value for students, researchers, and instructors interested in the area of iPS cell biology. … it serves as an excellent resource for those studying this topic and provides a chronological perspective, appropriately discussing many of the key applications and challenges.” (Thomas Bodenstine, Doody's Book Reviews, June 21, 2019)

Haruhisa Inoue, CiRA, Kyoto University, Japan; RIKEN BRC, Japan; RIKEN AIP, JAPANYukio Nakamura, RIKEN BioResource Center, Japan

• Introduction. Overview.- Disease Modeling. iPSCs for disease modeling.- Reprogramming cancer cells.- Recapitulating hematopoiesis in the lab.- Modeling cardiomyopathies with iPSCs.- Molecular Technologies. Controling cell state with intracellular biomarkers.- Genome editing of stem cells.- iPS Applications. iPSC-based cell therapy for eye diseases.- 3D models for organ development.- Drug discovery using iPSCs.- Direct differentiation of neural cells.

“The book is most appropriate for those with a basic understanding of molecular biology and stem cell function, with value for students, researchers, and instructors interested in the area of iPS cell biology. … it serves as an excellent resource for those studying this topic and provides a chronological perspective, appropriately discussing many of the key applications and challenges.” (Thomas Bodenstine, Doody's Book Reviews, June 21, 2019)