Mechanisms of Transcription

• Fundamental Aspects of T7 RNA Polymerase Structure and Mechanism.- Transcription by T7 RNA Polymerase.- Pribnow Box Recognition and Melting by Escherichia coli RNA Polymerase.- Extended —10 Promoters.- Promoter Selectivity Control of RNA Polymerase.- The Effect of High Pressure on Transcription and on the Structure and Activity of E. coli RNA Polymerase.- Ribosomal RNA Promoter-RNA Polymerase Interactions and rRNA Transcription in Escherichia coli.- Synergistic Activation of Transcription in E. coli.- Indirect Effects of DNA Sequence on Transcriptional Activation by Prokaryotic DNA Binding Proteins.- Transcriptional Activation by a Topologically Linkable Protein: Forging a Connection Between Replication and Gene Activity.- Translocation of DNA-Dependent E. coli RNA Polymerase During RNA Synthesis.- Stabilisation of DNA Microloops by FIS — A Mechanism for Torsional Transmission in Transcription Activation and DNA Inversion.- Transcription and DNA Topology in Eubacteria.- Modeling Large DNA Molecules: Long-Range Interactions and Regulation of Transcription.- Structure of the POU Domain.- Structural Studies of Eukaryotic Transcription Initiation.- Understanding SRY-Related 46X,Y Sex Reversal at the Atomic Level.- Nucleosomes and Transcription.- Antirepression, Potentiation and Activation of Promoters in Reconstituted Chromatin.- Acetylation, Activation and Toxicity; the Role of ADA/GCN5 Complex in Transcription.

"The editors are to be congratulated in assembling an excellent collection of contributions from very eminent authors. This book will make a splendid addition to the shelves of those interested in the biophysics, biochemistry and structural biology of transcription and its regulation." Heredity