Mechanisms and Emerging Therapies in Tremor Disorders

Giuliana Grimaldi, MD, PhD, is a neurologist.  She is affiliated with Unità Spinale, ASP Palermo, Italy. She is a member of the Society for Cerebellar Research (SRC).Mario Manto, MD, PhD is a neurologist. He is researcher at the FNRS-Belgium, Head of the Department of Neurology, CHU-Charleroi, and Professor of Neuroanatomy at U Mons.  He is the founding and current editor of the international journal The Cerebellum (Springer). He is the President of the Medical Board of Euro-Ataxia. He has founded the Society for Research on the Cerebellum.  He is editor of the Contemporary Clinical Neuroscience series (Springer).

• PART I: Fundamental Aspects.- Chapter 1. Definition of Tremor.- Chapter 2. Membrane Mechanisms of Tremor.- Chapter 3 Advances in the Genetics of Human Tremor.- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor.- PART II:Tremor in Clinical Practice.- Chapter 5. Physiologic Tremor.- Chapter 6. Rest Tremor.- Chapter 7. Postural Tremors.- Chapter 8. Isometric Tremor.- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor.- Chapter 10. Cerebellar lesions and tremor.- Chapter 11. Orthostatic Tremor.- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders.- Chapter 13 Tremor in Childhood.- Chapter 14. Metabolic Causes of Tremor.- Chapter 15. Drug-Induced Tremor.- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis.- PART III: Assessment of tremor.- Chapter 17. Signal Processing.- Chapter 18. Diffusion imaging in Tremor.- Chapter 19. The role of the noradrenergic system in tremor pathogenesis.- Chapter 20. Metabolic Networks in Parkinson’s Disease.- PART IV: Therapies.- Chapter 21. Deep brain stimulation for tremor.- Chapter 22 Mechatronic Devices for Upper Limb Tremor.