“It enables the reader to acquire a capability to construct and analyze biological systems. The mathematical exposition is clear and with detailed explanations of important ideas and interesting results. The book takes an expository approach where the continuous prose intersects with several carefully constructed diagrams and figures. … it contains an extensive list of references and can serve as a reference text for researchers in this field.” (Stéphanie Abou and Anita T. Layton, SIAM Review, Vol. 63 (4), December, 2021)“An appendix summarizes important mathematical background results. The treatment of both finite- and infinite-dimensional systems is a unique feature of the book … . the book remains largely a book on classical methods, though one of highest mathematical standards. The book is decidedly mathematical in style, with complete proofs of all results, stringent mathematical argumentation, and a traditional definition-theorem-proof structure. … this second edition of the classical text remains a highly valuable contribution to the field.” (Lars Grüne, SIAM Review, Vol. 63 (2), September, 2021)“This new edition should be a useful resource for students and researchers of control theory.” (IEEE Control Systems Magazine, Vol. 41 (2), April, 2021)