Jesse E. Adams, MD FACCUniversity of LouisvilleDivision of Cardiology100 Mallard CreekLouisville, KY 40202USA Fred Apple, PhDDepartment of Laboratory Medicine and PathologyHennepin County Medical Center and University of Minnesota School of MedicineMinneapolis, MNUSA Allan S. Jaffe, MDCardiovascular Division and Cardiovascular Research Institute and Division of Laboratory MedicineMayo Clinic and Medical SchoolRochester, MinnesotaUSA

• Contents. Contributors.Preface.Part 1 Cardiac troponins.1 Basics of cardiac troponin: practical aspects of assays, potential.analytical confounders, and clinical interpretation.Fred S. Apple (University of Minnesota School of Medicine).2 Diagnostic use of cardiac troponins in ST-segment elevation.myocardial infarction.Susanne Korff (Medizinische Universitätsklinik Heidelberg), Hugo A. Katus (Department of Cardiology), Evangelos Giannitsis (Department of Cardiology).3 Therapeutic implications of cardiac troponins in ST-segment.elevation and non-ST-segment elevation myocardial.infarction.Tracy Y. Wang, John M. Castor, L. Kristin Newby.4 Ischemic heart disease in the absence of overt coronary.artery disease.Allan S. Jaffe (Mayo Clinic).5 So you think you have a “false positive’’ troponin?.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).6 Use of cardiac troponin in patients in non-ischemic pathologies.and exposure to environmental toxins.Fred S. Apple (University of Minnesota School of Medicine).7 Cardiac troponins in patients with congestive heart failure.Jesse Adams (Jewish Hospital Heart and Lung Institute).8 Troponins and the critically Ill patient.Jose Antonio Perez (Mayo Clinic & Medical School), Luciano Babuin (Cardiovascular Division & Cardiovascular), Allan S. Jaffe (Mayo Clinic).9 Cardiac troponins and renal failure.Suresh Pothuru (University of Maryland), Christopher deFilippi (University of Maryland).10 Cardiac biomarkers: detection of in-hospital myocardial.reinfarction.Fred S. Apple (University of Minnesota School of Medicine).Part 2 Natriuretic peptides.11 The future: interpreting new guidelines for myocardial.infarction.Allan S. Jaffe (Mayo Clinic).12 Basics of natriuretic peptides: practical aspects of assays,.potential analytical confounders, and clinical interpretation.Alan H.B. Wu (San Francisco General Hospital).13 Natriruetic peptides in clinical practice.Alan Maisel (University of California).14 Outpatient evaluation for cardiovascular diseases using.natriuretic peptide testing.Aaron L. Baggish (Massachusetts General Hospital), James L. Januzzi (Harvard Medical School).15 Natriuretic peptides in patients with renal failure.Peter A. McCullough (William Beaumont Hospital).16 Congestive heart failure: treatment implications of natriuretic.peptides.W Frank Peacock (Emergency Cardiology Research).17 Utilizing multimarker strategies in patients who present with.congestive heart failure.Johannes Mair (Universitaetsklinik fuer Innere Medizin).Part 3 Contemporary markers of risk.18 Clinical integration of C-reactive protein for primary and.secondary risk factor stratification.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).19 Lipoprotein subfraction analysis using nuclear magnetic.resonance spectroscopy.William C. Cromwell (Presbyterian Center for Preventive Cardiology), Harold E. Bays (L-Marc Research Center), Peter P. Toth (Director of Preventive Cardiology).Index

"I think this is a good book and good value for money. It is fairly light reading and I found myself wanting to make notes and use it as a point of reference as it pulls things together well. Therefore, I would recommend it to others." (Cardiology News, February 2009)

Jesse E. Adams, MD FACCUniversity of LouisvilleDivision of Cardiology100 Mallard CreekLouisville, KY 40202USA Fred Apple, PhDDepartment of Laboratory Medicine and PathologyHennepin County Medical Center and University of Minnesota School of MedicineMinneapolis, MNUSA Allan S. Jaffe, MDCardiovascular Division and Cardiovascular Research Institute and Division of Laboratory MedicineMayo Clinic and Medical SchoolRochester, MinnesotaUSA

• Contents. Contributors.Preface.Part 1 Cardiac troponins.1 Basics of cardiac troponin: practical aspects of assays, potential.analytical confounders, and clinical interpretation.Fred S. Apple (University of Minnesota School of Medicine).2 Diagnostic use of cardiac troponins in ST-segment elevation.myocardial infarction.Susanne Korff (Medizinische Universitätsklinik Heidelberg), Hugo A. Katus (Department of Cardiology), Evangelos Giannitsis (Department of Cardiology).3 Therapeutic implications of cardiac troponins in ST-segment.elevation and non-ST-segment elevation myocardial.infarction.Tracy Y. Wang, John M. Castor, L. Kristin Newby.4 Ischemic heart disease in the absence of overt coronary.artery disease.Allan S. Jaffe (Mayo Clinic).5 So you think you have a “false positive’’ troponin?.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).6 Use of cardiac troponin in patients in non-ischemic pathologies.and exposure to environmental toxins.Fred S. Apple (University of Minnesota School of Medicine).7 Cardiac troponins in patients with congestive heart failure.Jesse Adams (Jewish Hospital Heart and Lung Institute).8 Troponins and the critically Ill patient.Jose Antonio Perez (Mayo Clinic & Medical School), Luciano Babuin (Cardiovascular Division & Cardiovascular), Allan S. Jaffe (Mayo Clinic).9 Cardiac troponins and renal failure.Suresh Pothuru (University of Maryland), Christopher deFilippi (University of Maryland).10 Cardiac biomarkers: detection of in-hospital myocardial.reinfarction.Fred S. Apple (University of Minnesota School of Medicine).Part 2 Natriuretic peptides.11 The future: interpreting new guidelines for myocardial.infarction.Allan S. Jaffe (Mayo Clinic).12 Basics of natriuretic peptides: practical aspects of assays,.potential analytical confounders, and clinical interpretation.Alan H.B. Wu (San Francisco General Hospital).13 Natriruetic peptides in clinical practice.Alan Maisel (University of California).14 Outpatient evaluation for cardiovascular diseases using.natriuretic peptide testing.Aaron L. Baggish (Massachusetts General Hospital), James L. Januzzi (Harvard Medical School).15 Natriuretic peptides in patients with renal failure.Peter A. McCullough (William Beaumont Hospital).16 Congestive heart failure: treatment implications of natriuretic.peptides.W Frank Peacock (Emergency Cardiology Research).17 Utilizing multimarker strategies in patients who present with.congestive heart failure.Johannes Mair (Universitaetsklinik fuer Innere Medizin).Part 3 Contemporary markers of risk.18 Clinical integration of C-reactive protein for primary and.secondary risk factor stratification.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).19 Lipoprotein subfraction analysis using nuclear magnetic.resonance spectroscopy.William C. Cromwell (Presbyterian Center for Preventive Cardiology), Harold E. Bays (L-Marc Research Center), Peter P. Toth (Director of Preventive Cardiology).Index

"I think this is a good book and good value for money. It is fairly light reading and I found myself wanting to make notes and use it as a point of reference as it pulls things together well. Therefore, I would recommend it to others." (Cardiology News, February 2009)

Jesse E. Adams, MD FACCUniversity of LouisvilleDivision of Cardiology100 Mallard CreekLouisville, KY 40202USA Fred Apple, PhDDepartment of Laboratory Medicine and PathologyHennepin County Medical Center and University of Minnesota School of MedicineMinneapolis, MNUSA Allan S. Jaffe, MDCardiovascular Division and Cardiovascular Research Institute and Division of Laboratory MedicineMayo Clinic and Medical SchoolRochester, MinnesotaUSA

• Contents. Contributors.Preface.Part 1 Cardiac troponins.1 Basics of cardiac troponin: practical aspects of assays, potential.analytical confounders, and clinical interpretation.Fred S. Apple (University of Minnesota School of Medicine).2 Diagnostic use of cardiac troponins in ST-segment elevation.myocardial infarction.Susanne Korff (Medizinische Universitätsklinik Heidelberg), Hugo A. Katus (Department of Cardiology), Evangelos Giannitsis (Department of Cardiology).3 Therapeutic implications of cardiac troponins in ST-segment.elevation and non-ST-segment elevation myocardial.infarction.Tracy Y. Wang, John M. Castor, L. Kristin Newby.4 Ischemic heart disease in the absence of overt coronary.artery disease.Allan S. Jaffe (Mayo Clinic).5 So you think you have a “false positive’’ troponin?.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).6 Use of cardiac troponin in patients in non-ischemic pathologies.and exposure to environmental toxins.Fred S. Apple (University of Minnesota School of Medicine).7 Cardiac troponins in patients with congestive heart failure.Jesse Adams (Jewish Hospital Heart and Lung Institute).8 Troponins and the critically Ill patient.Jose Antonio Perez (Mayo Clinic & Medical School), Luciano Babuin (Cardiovascular Division & Cardiovascular), Allan S. Jaffe (Mayo Clinic).9 Cardiac troponins and renal failure.Suresh Pothuru (University of Maryland), Christopher deFilippi (University of Maryland).10 Cardiac biomarkers: detection of in-hospital myocardial.reinfarction.Fred S. Apple (University of Minnesota School of Medicine).Part 2 Natriuretic peptides.11 The future: interpreting new guidelines for myocardial.infarction.Allan S. Jaffe (Mayo Clinic).12 Basics of natriuretic peptides: practical aspects of assays,.potential analytical confounders, and clinical interpretation.Alan H.B. Wu (San Francisco General Hospital).13 Natriruetic peptides in clinical practice.Alan Maisel (University of California).14 Outpatient evaluation for cardiovascular diseases using.natriuretic peptide testing.Aaron L. Baggish (Massachusetts General Hospital), James L. Januzzi (Harvard Medical School).15 Natriuretic peptides in patients with renal failure.Peter A. McCullough (William Beaumont Hospital).16 Congestive heart failure: treatment implications of natriuretic.peptides.W Frank Peacock (Emergency Cardiology Research).17 Utilizing multimarker strategies in patients who present with.congestive heart failure.Johannes Mair (Universitaetsklinik fuer Innere Medizin).Part 3 Contemporary markers of risk.18 Clinical integration of C-reactive protein for primary and.secondary risk factor stratification.Jesse E. Adams (Jewish Hospital Heart and Lung Institute).19 Lipoprotein subfraction analysis using nuclear magnetic.resonance spectroscopy.William C. Cromwell (Presbyterian Center for Preventive Cardiology), Harold E. Bays (L-Marc Research Center), Peter P. Toth (Director of Preventive Cardiology).Index

"I think this is a good book and good value for money. It is fairly light reading and I found myself wanting to make notes and use it as a point of reference as it pulls things together well. Therefore, I would recommend it to others." (Cardiology News, February 2009)