There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Committee on Mapping and Sequencing the Human Genome, National Research Council
1 Front Matter; 2 1 Executive Summary; 3 2 Introduction; 4 3 Implications for Medicine and Science; 5 4 Mapping; 6 5 Sequencing; 7 6 The Collection, Analysis, and Distribution of Information and Materials; 8 7 Implementation and Management Strategies; 9 8 Implications for Society; 10 Appendix A Glossary; 11 Appendix B Curricula Vitae of Committee Members; 12 Appendix C Invited Speakers at Committee Meetings; 13 Index
National Research Council, Division on Earth and Life Studies, Board on Life Sciences, Committee on Metagenomics: Challenges and Functional Applications
National Research Council, Division of Behavioral and Social Sciences and Education, Institute of Medicine, and Families Board on Children, Youth, Steve Olson
National Research Council, Division on Earth and Life Studies, Board on Agriculture and Natural Resources, Committee on Animal Nutrition, Subcommittee on Dog and Cat Nutrition
National Research Council, Division of Behavioral and Social Sciences and Education, Commission on Behavioral and Social Sciences and Education, and Statistical Sciences Committee on AIDS Research and the Behavioral, Social, Lincoln E. Moses, Heather G. Miller, Charles F. Turner
National Research Council, Division on Engineering and Physical Sciences, Commission on Engineering and Technical Systems, Division of Natural Hazard Mitigation, Committee on Natural Disasters
National Research Council, Division on Engineering and Physical Sciences, Commission on Engineering and Technical Systems, Division of Natural Hazard Mitigation, Committee on Natural Disasters
National Research Council, Division on Earth and Life Studies, Environment and Resources Commission on Geosciences, Board on Environmental Studies and Toxicology, Committee to Review the Outer Continental Shelf Environmental Studies Program, Ecology Panel
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
The Royal Society, National Academy of Sciences, National Academy of Medicine, International Commission on the Clinical Use of Human Germline Genome Editing
and Medicine National Academies of Sciences, Engineering, Division of Behavioral and Social Sciences and Education, Health and Medicine Division, Committee on Population, Board on Health Sciences Policy, and Ancestry as Population Descriptors in Genomics Research Committee on the Use of Race, Ethnicity
National Research Council, Institute of Medicine, Board on Health Care Services, National Cancer Policy Forum, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, and Translation Forum on Drug Discovery, Development, Division on Earth and Life Studies, Board on Life Sciences, Policy and Global Affairs, and Law Committee on Science, Technology, Anne-Marie Mazza, Mary Fraker
Institute of Medicine, Board on Health Sciences Policy, Board on Health Care Services, Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials, Gilbert S. Omenn, Sharly J. Nass, Christine M. Micheel
Center for Medical Technology Policy, Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Steve Olson, Adam C. Berger
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
Institute of Medicine, Board on Health Sciences Policy, Committee on the Independent Review and Assessment of the Activities of the NIH Recombinant DNA Advisory Committee, Lawrence O. Gostin, Bruce M. Altevogt, Rebecca N. Lenzi
Center for Medical Technology Policy, Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Steve Olson, Adam C. Berger
National Research Council, Institute of Medicine, Board on Health Care Services, National Cancer Policy Forum, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, and Translation Forum on Drug Discovery, Development, Division on Earth and Life Studies, Board on Life Sciences, Policy and Global Affairs, and Law Committee on Science, Technology, Anne-Marie Mazza, Mary Fraker
and Medicine National Academies of Sciences, Engineering, National Academy of Medicine, National Academy of Sciences, and Ethical Considerations Committee on Human Gene Editing: Scientific, Medical
Institute of Medicine, Board on Health Sciences Policy, Roundtable on Translating Genomic-Based Research for Health, Adam C. Berger, Steve Olson, Samuel G. Johnson, Sarah H. Beachy
Institute of Medicine, Board on Health Sciences Policy, Board on Health Care Services, Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials, Gilbert S. Omenn, Sharly J. Nass, Christine M. Micheel
and Medicine National Academies of Sciences, Engineering, Health and Medicine Division, Board on Health Care Services, National Cancer Policy Forum, Board on Health Sciences Policy, Roundtable on Genomics and Precision Health, Sarah Beachy, Meredith Hackmann, Kathryn Asalone, Theresa M. Wizemann
and Medicine National Academies of Sciences, Engineering, Health and Medicine Division, Division on Earth and Life Studies, Board on Health Sciences Policy, Board on Life Sciences, Toward Sequencing and Mapping of RNA Modifications Committee
Institute of Medicine, Board on Health Sciences Policy, Committee on the Independent Review and Assessment of the Activities of the NIH Recombinant DNA Advisory Committee, Lawrence O. Gostin, Bruce M. Altevogt, Rebecca N. Lenzi