Mammalian Sterols

Novel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids

Inbunden, Engelska, 2020

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This book provides a comprehensive description of sterols and their novel biological roles in mammalian signaling, the book covers their biosynthesis and structure, describes sterol receptor -mediated actions, their tissue distribution and their role in disease.

Produktinformation

Utgivningsdatum2020-08-11
Mått155 x 235 x 15 mm
Vikt474 g
FormatInbunden
SpråkEngelska
Antal sidor171
FörlagSpringer Nature Switzerland AG
ISBN9783030396831

Tillhör följande kategorier

Däggdjur inom Djur och Natur
Biologi inom Naturvetenskap och teknik
Biokemi inom Naturvetenskap och teknik
Cellbiologi inom Naturvetenskap och teknik
Däggdjur inom Naturvetenskap och teknik

Damjana Rozman is full Professor of Biochemistry and Molecular Biology at the Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Slovenia and Head of the Centre for Functional Genomcis and Bio-Chips (CFGBC).Rolf Gebhardt is Professor (em.) of Biochemistry at the Rudolf Schönheimer Institute of Biochemistry, Department of General Biochemistry, University of Leipzig, Faculty of Medicine, Leipzig, Germany.

Sterols from the post-lanosterol part of cholesterol synthesis – novel signaling players.- Genetic variability in cholesterol metabolism.- Side-chain oxidized oxysterols in health and disease.- Bile acids and TGR5 (Gpbar1) signaling.- Bile acids as regulatory signalling molecules.- Oxysterols and bile acid act as signaling molecules that regulate cholesterol homeostasis: nuclear receptors LXR, FXR, and fibroblast growth factor 15/19.- Cytochrome P450 Metabolism Leads to Novel Biological Sterols and Other Steroids.