Mammalian Genomics

Inbunden, Engelska, 2004

AvAnatoly Ruvinsky,Jennifer A. Marshall Graves,Anatoly Ruvinsky,Jennifer Marshall Graves

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Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals. Topics covered include structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, evolution of DNA sequences, comparative chromosome mapping and painting, genome databases, gene prediction and the use of genomic information to understand inherited diseases. Contributors include leading researchers from Europe, USA, Australia and Japan.

Produktinformation

Utgivningsdatum2004-12-20
Mått172 x 244 x 37 mm
Vikt1 456 g
FormatInbunden
SpråkEngelska
Antal sidor624
FörlagCABI Publishing
ISBN9780851999104

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Since graduation from Novosibirsk State University (Russia) in 1969 A. Ruvinsky has been working in several fields of genetics for more than 40 years. He received his PhD in 1974 and Dr.Sc. in 1985. In 1986 A. Ruvinsky was elected as head of laboratory of animal genetics and 1988 as Vice Director of the Institute of Cytology and Genetics of Russian Academy of Sciences. In 1993 A. Ruvinsky joined the University of New England, Australia. Professor Ruvinsky published more than 100 refereed papers in leading genetic journals and edited 14 books so far. This includes the series of books on mammalian genetics, which currently undergoes 2nd edition. His conceptual book "Genetics and Randomness" was published in 2009.

Part 1: Organization of the Mammalian Genome 1: Linkage mapping, 2: Mapping genomes at the chromosome level, 3: Mapping genomes at the molecular level, 4: DNA sequence of the human and other mammalian genomes, Part 2: Expression of the Mammalian Genome 5: The transcriptome, 6: The proteome, 7: The epigenome - epigenetic regulation of gene expression in mammalian species, 8: Regulation of genome activity and genetic networks in mammals, 9: Inducing alterations in the mammalian genome for investigating the function of genes, Part 3: Evolution of the Mammalian Genome 10: Mammalian genomes in context, 11: Elements and mechanisms of genome change, 12: DNA sequence evolution and phylogenetic footprinting, 13: The evolution of the mammalian karyotype, 14: Comparative gene mapping and chromosome painting in mammals and the reconstruction of the ancestral mammalian karyotype, Part 4: Genome Analysis and Bioinformatics 15: Bioinformatics: from computational analysis through to integrated systems, 16: Genetic databases, 17: Gene predictions and annotations, Part 5: The Fruits of Mammalian Genomics 18: Genomic research and progress in understanding inherited disorders in humans and other mammals, 19: Pharmacogenomics, 20: Genome scanning for quantitative trait loci, 21: Mammalian population genetics and genomics,