MALDI Mass Spectrometry for Synthetic Polymer Analysis

Liang Li, PhD, is a Professor of Chemistry and a Canada Research Chair in Analytical Chemistry at the University of Alberta. He is an Editor of Analytical Chimica Acta and a member of the Advisory Boards for the Journal of the American Society for Mass Spectrometry, Canadian Journal of Chemistry, and Current Analytical Chemistry.

• PREFACE viiCONTRIBUTORS ixCHAPTER 1 OVERVIEW OF MS AND MALDI MS FOR POLYMER ANALYSIS 1Liang LiCHAPTER 2 IONIZATION PROCESSES AND DETECTION IN MALDI-MS OF POLYMERS 9Renato ZenobiCHAPTER 3 TIME-OF-FLIGHT MASS SPECTROMETRY FOR POLYMER CHARACTERIZATION 27Liang Li and Randy M. WhittalCHAPTER 4 POLYMER ANALYSIS WITH FOURIER TRANSFORM MASS SPECTROMETRY 53Sabine Borgmann and Charles L. WilkinsCHAPTER 5 TANDEM MASS SPECTROMETRY AND POLYMER ION DISSOCIATION 85Michael J. Polce and Chrys WesdemiotisCHAPTER 6 CONVENTIONAL MALDI SAMPLE PREPARATION 129Kevin G. Owens and Scott D. HantonCHAPTER 7 SOLVENT-FREE MALDI SAMPLE PREPARATION 159Sarah TrimpinCHAPTER 8 MALDI MASS SPECTROMETRY FOR THE QUANTITATIVE DETERMINATION OF POLYMER MOLECULAR MASS DISTRIBUTION 187Charles M. Guttman and William E. WallaceCHAPTER 9 NEW APPROACHES TO DATA REDUCTION IN MASS SPECTROMETRY 205William E. Wallace, Anthony J. Kearsley, and Charles M. GuttmanCHAPTER 10 MALDI-MS/MS FOR POLYMER STRUCTURE AND COMPOSITION ANALYSIS 219Anthony T. JacksonCHAPTER 11 LC-MALDI MS FOR POLYMER CHARACTERIZATION 247Steffen M. Weidner and Jana FalkenhagenCHAPTER 12 MALDI MS APPLICATIONS FOR INDUSTRIAL POLYMERS 267Scott D. Hanton and Kevin G. OwensINDEX 289

"The primary audience will be beginning graduate students (or advanced undergraduates) who are starting research on MALDI of polymers. It will also be of great value for industrial chemists who work in polymer MALDI. I would also recommend it to polymer chemists who want to understand how MALDI can help them in their work." (Anal Bioanal Chem, 2010) "Overall, I highly recommend this book for any polymer scientist with access to MALDI-MS as it will aid in the better planning of experiments and interpretation of the results. This is definitely a book for beginning graduate students in the field and for MS facility managers who are constantly exposed to a wide variety of samples, with synthetic polymers being among them." (JACS, 2010)