Magnetic Resonance Imaging in Deep Brain Stimulation

Alexandre Boutet, MD, PhD, FRCPC is a neuroradiology fellow at the University of Toronto in the Medical Imaging Department. His research focuses on investigating brain modulation (e.g. deep brain stimulation) and MR-guided focused ultrasound (MRgFUS) using advanced neuroimaging techniques such as fMRI and DTI.  Dr. Andres M. Lozano, OC, MD, PhD, FRCSC, FRSC, FCAHS is a University Professor and the past Dan Family Chairman of Neurosurgery at the University of Toronto.  He holds the Alan & Susan Hudson Cornerstone Chair in Neurosurgery at Toronto Western Hospital, University Health Network. He is best known for his work in the field of Deep Brain Stimulation (DBS) and Magnetic Resonance-guided Focused Ultrasound (MRgFUS).  His team has mapped cortical and subcortical circuits in the human brain and has discovered and advanced novel therapies for Parkinson’s disease, depression, dystonia, anorexia, Huntington’s disease and Alzheimer’s disease.   Dr. Lozano has over 750 manuscript publications, co-edited 10 books and over 100 book chapters, and serves on the boards of several international organizations.  He is the all-time most highly cited neurosurgeon in the world (Clarivate).  Dr. Lozano has delivered over 50 named international lectures and has received a number of honors including Doctor Honoris Causa from the University of Sevilla, the Olivecrona Medal, Margolese Brain Prize, Salk Award, Pioneer in Medicine Award and the Dandy Medal.  He has been elected to the Royal Society of Canada, has received the Order of Spain and is an Officer of the Order of Canada.

• Historical perspective on the roles of imaging in DBS.- Overview of the clinical aspects of DBS.- Preoperative planning of DBS surgery with MRI.- MRI safety in patients with DBS.- Postoperative MRI applications in patients with DBS.- Prospective acquisition of fMRI in patients with DBS.- Future directions.