This book constitutes the refereed proceedings of the 6th International Conference on Machine Learning for Networking, MLN 2023, held in Paris, France, during November 28–30, 2023.The 18 full papers included in this book were carefully reviewed and selected from 34 submissions. The conference aims at providing a top forum for researchers and practitioners to present and discuss new trends in machine learning, deep learning, pattern recognition and optimization for network architectures and services.