Lung Cancer and Personalized Medicine

Aamir Ahmad, PhD, is a Scientist at the Wayne State University School of Medicine, Department of Pathology, and the Karmanos Cancer Institute. He has been a member of leading cancer organizations such as the American Association for Cancer Reseasrch and the Union for International Cancer Control. In addition to serving as a reviewer for a number of peer-reviewed scientific journals, he is currently a Section Editor for the journal PLoS ONE, for which he is responsible for policy drafts and the identification and management of special issues. Dr. Ahmad has published more than 100 scientific papers and has authored numerous book chapters. In addition to the current volume Dr. Ahmad served as the editor of two volumes published by Springer. Shirish M. Gadgeel, M.D. a Professor in the Department of Oncology at Karmanos Institute/Wayne State University in Detroit. He is the co-leader of the Molecular Therapeutics Program of Karmanos Cancer Institute and the leader of the Multidisciplinary Thoracic Oncology team. Dr. Gadgeel is a member of several professional societies, including the American Society of Clinical Oncology and the International Association for the Study of Lung Cancer. He currently serves on the Editorial Board of the journals Cancer and Clinical Lung Cancer. Dr. Gadgeel is a Principal Investigator of several trials focused on the treatment of Lung Cancer, and has published more than 80 scientific papers

• 1 Lung Cancer Statistics.- 2 Epidemiology of Lung Cancer.- 3 Lung Cancer In Never Smokers.- 4 Immune Therapy.- 5 Anti-angiogenesis in personalized therapy of lung cancer.- 6 Target therapy in Lung Cancer.- 7 Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors and Therapeutic Approaches: an update.- 8 KRAS-Mutant Lung Cancers in the Era of Targeted Therapy.- 9 Anaplastic Lymphoma Kinase (ALK) Signaling in Lung Cancer.- 10 Chemotherapy Resistance in Lung Cancer.- 11 Current state of metal-based drugs for the efficient therapy of lung cancers and lung metastases.

“The aim of this book is to discuss current knowledge about lung cancer with a specific focus on non-small-cell lung cancer (NSCLC). … The intended audience is established researchers, clinicians, healthcare professionals, and students in the medical and scientific community. … The authors have successfully compiled a well-written, comprehensive, and robust book about NSCLC … .” (Karen L. Reckamp, Doody’s Book Reviews, August, 2016)