Del 1 i serien Perspectives in Supramolecular Chemistry

Lock-and-Key Principle

The State of the Art--100 Years On

Inbunden, Engelska, 1994

9 559 kr

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Published 100 years after Emil Fischer first proposed the lock-and-key principle, this volume provides a complete review of the subject to date and offers suggestions for futher research. The major impact of the lock-and-key principle on the chemical, biomedical and materials sciences is discussed by leaders in the field, with chapters dedicated to molecular recognition, nucleic acid and protein chemistry, crystallography and the development of Emil Fischer's initial ideas. The Lock-and-Key Principle is the most up-to-date review of progress in supramolecular chemistry and the lock-and-key principle and will become the essential guide to the past, present and future of this remarkable principle.

Produktinformation

Utgivningsdatum1994-12-20
Mått165 x 239 x 27 mm
Vikt680 g
FormatInbunden
SpråkEngelska
SeriePerspectives in Supramolecular Chemistry
Antal sidor336
FörlagJohn Wiley & Sons Inc
ISBN9780471939023

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Contributors viiPreface ix1 Emil Fischer’s Lock-and-Key Hypothesis after 100 Years—Towards a Supracellular Chemistry 1Friedrich Cramer2 Molecular Recognition in Biology: Models for Analysis of Protein-Ligand Interactions 25Doron Lancet, Amnon Horovitz and Ephraim Katchalski-Katzir3 New Biocatalysts via Chemical Modification 73Ian M. Bell and Donald Hilvert4 Oligonucleotides: Superspecific Ligands for Targeting Nucleic Acids and Proteins and Development of Molecular Devices 89V. V. Vlassov5 Macrocycles and Antibodies as Catalysts 149D. B. Smithrud and S. J. Benkovic6 Lock-and-Key Processes at Crystalline Interfaces: Relevance to the Spontaneous Generation of Chirality 173Isabelle Weissbuch, Ronit Popovitz-Biro, Leslie Leiscrowitz and Meir Lahav7 A Model of the Origin of Life and Perspectives in Supramolecular Engineering 247H. Kuhn and J. Waser8 Perspectives in Supramolecular Chemistry—From the Lock-and-Key Image to the Information Paradigm 307Jean-Marie LehnIndex 319