In this issue of Gastroenterology Clinics, guest editors Drs. Ivo Tzvetanov and Pierpaolo Di Cocco bring their considerable expertise to the topic of Intestinal and Living Donor Transplantation. Top experts offer a timely, comprehensive exploration of cutting-edge advances in transplant surgery, donor ethics, and patient outcomes-topics of increasing importance for gastroenterologists as transplant indications broaden and surgical innovations evolve. This issue is particularly relevant as living donor transplant programs expand and gastroenterologists play a central role in pre- and post-transplant care, referral, and surveillance of both recipients and donors.