Life-Span Extension

• Yeast.- Reprogramming Cell Survival and Longevity: The Role of Tor, Sch9, Ras, and Sir2.- Caenorhabditis elegans.- 2 Common Aging Mechanisms: Energy Metabolism and Longevity in Caenorhabditis elegans.- 3 Conserved Mechanisms of Life-Span Regulation and Extension in Caenorhabditis elegans.- Drosophila melanogaster.- The Genetic Architecture of Longevity.- Mild Stress and Life Extension in Drosophila melanogaster.- Rodents.- Global Food Restriction.- Growth Hormone and Aging in Mice.- Comparative Biology of Aging.- Exploiting Natural Variation in Life Span to Evaluate Mechanisms of Aging.- Slow Aging: Insights from an Exceptionally Long-Lived Rodent, the Naked Mole-Rat.- Life Extension in the Short-Lived Fish Nothobranchius furzeri.- Aging in Humans.- Aging and Longevity in Animal Models and Humans.

From the reviews: "This multiauthored book reviews the mechanisms of life-span extension across the animal kingdom, including man. ... The audience here is researchers into the nature of aging and longevity. Many scientists looking at redox reactions in the body find themselves ultimately researching the nature of aging. For them, this is a useful guide. ... This compact, well-edited book is a timely review of a complex subject." (David O. Staats, Doody's Review Service, April, 2010)