Leydig Cell in Health and Disease

• Historical.- A History of Leydig Cell Research.- Cell Biology.- Structural and Histological Analysis of Leydig Cell Steroidogenic Function.- Fetal Leydig Cells.- Regulation of Leydig Cells During Pubertal Development.- The Human Leydig Cell.- Dynamics of Leydig Cell Regeneration After EDS.- Aging and the Decline of Androgen Production.- Steroidogenesis.- Regulation of Leydig Cell Cholesterol Metabolism.- The Role of StAR in Leydig Cell Steroidogenesis.- Steroidogenic Enzymes in Leydig Cells.- Development of Leydig Cell Steroidogenesis.- Peripheral Testosterone Metabolism.- Leydig Cell Aromatase.- The Role of Estrogen Sulfotransferase in Leydig Cells.- Endocrinology of Leydig Cells in Nonmammalian Vertebrates.- Regulation.- The Luteinizing Hormone Receptor.- Insights Into Leydig Cell Function From Mice With Genetically Modified Gonadotropin Action.- Growth Factors in Leydig Cell Function.- Insulin-Like Peptide 3 in Leydig Cells.- Neuronal Signaling Molecules and Leydig Cells.- Regulation of Leydig Cell Function as it Pertains to the Inflammatory Response.- Activins and Leydig Cell Development Differentiation, and Disease.- Transcription Factors as Regulators of Gene Expression During Leydig Cell Differentiation and Function.- Androgen Receptor in Leydig Cell Function and Development.- Physiology and Applied Aspects.- Fluid Exchange and Transport of Hydrophilic Factors in the Testis.- Immortalized Leydig Cell Lines as Models for Studying Leydig Cell Physiology.- Induction of Leydig Cell Tumors by Xenobiotics.- Environmental Factors That Disrupt Leydig Cell Steroidogenesis.- The Leydig Cell as a Target for Male Contraception.- Clinical Evaluation of Leydig Cell Function.

From the reviews: "Part of the Series Contemporary Endocrinology, this volume reviews in 5 parts and 30 chapters written by an international team aspects of Leydig cell biology, physiology and clinic. The book has many high quality illustrations, some in color. Of interest to endocrinologists and andrologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)