Del i serien Ernst Schering Foundation Symposium Proceedings

Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Inbunden, Engelska, 2003

AvA. Hamann,Khusru Asadullah,A. Schottelius

2 209 kr

Beställningsvara. Skickas inom 10-15 vardagar. Fri frakt för medlemmar vid köp för minst 249 kr.

Finns i fler format (1)

Häftad

2 209 kr

Skickas inom 10-15 vardagar

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Produktinformation

Utgivningsdatum2003-10-07
Mått140 x 216 x 19 mm
Vikt529 g
FormatInbunden
SpråkEngelska
SerieErnst Schering Foundation Symposium Proceedings
Antal sidor242
Upplaga2004
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783540401124

Tillhör följande kategorier

Fysiologi inom Medicin

1 Selectin Ligands on T Cells.- 2 Skin Homing T Cells.- 3 Cutaneous Lymphocyte Localization in the Pathogenesis of Psoriasis.- 4 The Role of Fucosylation in Leukocyte Adhesion Deficiency II.- 5 Substrate Specificity and Synthetic Use of Glycosyltransferases.- 6 Control of FucT-VII Expression in CD4+ T Cells.- 7 Selectin Avidity Modulation by Chemokines at Subsecond Endothelial Contacts: A Novel Regulatory Level of Leukocyte Trafficking.- 8 Interactions of Selectins with PSGL-1 and Other Ligands.- 9 Saturation Transfer Difference NMR Spectroscopy to Identify Ligand Epitopes and Binding Specificities.- 10 Chemokine Receptor Antagonists from Discovery to the Clinic.- 11 The Role of Chemokines in Inflammatory Skin Diseases.- Previous Volumes Published in This Series.

Mer från samma författare

Lessing's Laokoon (1878)

Gotthold Ephraim Lessing, A Hamann

Häftad, 2008

579 kr

Lessing's Laokoon

A Hamann

Häftad, 2019

389 kr

Mer från samma serie

Human Gene Therapy: Current Opportunities and Future Trends

G. M. Rubanyi, S. Ylä-Herttuala

Inbunden, 2003

2 949 kr

From Morphological Imaging to Molecular Targeting

Markus Schwaiger, Ludger Dinkelborg, Hermann Schweinfurth

Inbunden, 2004

2 209 kr

Molecular Imaging

A. Bogdanov, Alexei Bogdanov, Kai Licha

Inbunden, 2004

2 939 kr

Animal Models of T Cell-Mediated Skin Diseases

T. Zollner, Harald Renz, Khusru Asadullah

Inbunden, 2004

2 209 kr

Biocombinatorial Approaches for Drug Finding

W. Wohlleben, T. Spellig, B. Müller-Tiemann

Inbunden, 2004

2 139 kr

Regenerative and Cell Therapy

A. Keating, K. Dicke, N. Gorin, R. Weber, H. Graf

Inbunden, 2004

1 429 kr

New Mechanisms for Tissue-Selective Estrogen-Free Contraception

H. B. Croxatto, H.B. Croxatto, R. Schürmann, U. Fuhrmann, I. Schellschmidt

Inbunden, 2005

2 209 kr

Promises and Challenges of Regenerative Medicine

J. Morser, John Morser, S. -I. Nishikawa

Inbunden, 2005

1 479 kr

Del 55

Chronic Viral and Inflammatory Cardiomyopathy

Schultheiss, H. Schultheiss, Heinz-Peter Schultheiss, Joachim-Friedrich Kapp, Georg Grötzbach

Inbunden, 2005

2 209 kr

Del 12

Von der Wahrnehmung zur Erkenntnis - From Perception to Understanding

Monika Lessl, Jürgen Mittelstraß

Inbunden, 2005

809 kr

Du kanske också är intresserad av