Key Heterocycle Cores for Designing Multitargeting Molecules

Dr. Om Silakari is an assistant professor in the Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India. He received his Ph.D. degree from Dr. Hari Singh Gour University, India and has been teaching and researching in this area for over 10 years. His research areas include computer-assisted drug designing (CADD) of new anti-inflammatory, antidiabetic and anticancer targets, and the synthesis of new lead molecules. In addition to supervising multiple M. Pharm. and PhD students, he has authored two books and published over 60 papers in international journals. Dr Silakari is an active reviewer for many international journals, has been awarded funding for several research projects, and regularly delivers talks at both national and international conferences.

• 1. Multitargeting heterocycles – An improved and rational chemical probes for multifactorial diseases2. Benzimidazole: Journey from a single targeting to a multitargeting nucleus3. Acridines: A relatively lesser explored heterocycle for multifactorial diseases4. Flavone: An important scaffold for medicinal chemistry5. Thiazolidine-2,4-dione: a potential weapon for targeting multiple pathological conditions6. Oxindole: A nucleus enriched with multi-targeting potential against complex disorders7. Thiazine: A Versatile Heterocyclic Scaffold for Multifactorial Diseases8. Indole: As multi-target directed ligands in medicinal chemistry9. Triazoles: Multidimensional 5-membered nucleus for designing multitargeting agents 10. Benzoxazolinone: A scaffold with diverse pharmacological significance