Kaufman's Atlas of Mouse Development Supplement

Gillian Morriss-Kay is Emeritus Professor of Developmental Anatomy at the University of Oxford, where she taught embryology, histology and anatomy to medical students. Her research goal, using first rat, then mouse embryos, was to enhance understanding of normal and abnormal human development, especially of the craniofacial region and neural tube. This led to collaborative mouse-human work on the developmental genetics and morphogenesis of craniosynostosis. She was editor of the Journal of Anatomy for ten years. Shankar Srinivas has a research career spanning 30 years, focusing on mouse developmental genetics (kidney, peri-implantation embryology, gastrulation and early cardiogenesis). More recently his work involves also using human embryos to understand early cell type diversification and cardiogenesis. He teaches anatomy and embryology to medical students. In 2004 Dr. Srinivas started his independent group at the University of Oxford as a Wellcome Trust Career Development Fellow and as Zeitlyn Fellow and Tutor in Medicine at Jesus College. In 2016 he became Professor of Developmental Biology. His research group studies how the coordinated cell movements that shape the early mammalian embryo prior to and during gastrulation are controlled and understanding how the heart forms and starts to beat. His group takes a multidisciplinary and collaborative approach to address these questions, using techniques spanning molecular genetics, lightsheet and confocal time-lapse imaging, single cell approaches, proteomics and embryo explant culture.

• 1. Introduction2. Coronal sections3. A Revised staging of mouse development before organogenesis4. Establishment of early embryonic lineages and the basic body plan5. Early organogenesis: placing and elaborating the organ primordia6. Placenta formation – Developmental milestones toward the establishment of a functional feto-maternal interface7. Spatio-temporal dynamics of mouse heart tube development8. Establishment of a double blood circulation in the developing mouse heart9. Development of the hematopoietic system10. Thymus development11. Gastrointestinal tract12. Development of the pancreas13. The reproductive system14. Development of the respiratory system15. The urinary system16. Integument and associated integumentary appendages17. The axial musculoskeletal system18. Spinal cord and peripheral nervous system19. Limb development20. The craniofacial region21. Regulatory mechanisms of palate and tongue development22. The developmental anatomy of teeth23. Brain development24. The visual system25. Development of the mouse inner ear26. Olfactory system embryonic development27. The Mouse Developmental Anatomy Ontology (EMAPA) and the Gene Expression Database for Mouse Development (GXD)28. Digital graphical resources and developmental anatomy in the mouse29. The informatics of developmental phenotypes