Isolation and Molecular Characterization of Circulating Tumor Cells

Häftad, Engelska, 2018

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Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities.

Produktinformation

Utgivningsdatum2018-08-02
Mått155 x 235 x 18 mm
Vikt487 g
FormatHäftad
SpråkEngelska
SerieAdvances in Experimental Medicine and Biology
Antal sidor301
FörlagSpringer International Publishing AG
ISBN9783319857879

Tillhör följande kategorier

Onkologi inom Medicin

Preface.- Circulating Tumor Cells as Cancer Biomarkers.- Strategies for Isolation and Molecular Profiling of Circulating Tumor Cells.- Aptamer-Based Methods for Detection of Circulating Tumor Cells and Their Potential for Personalized Diagnostics.- Development of a Protocol for Single-Cell Analysis of Circulating Tumor Cells in Patients with Solid Tumors.- Flow Cytometric Methods for Circulating Tumor Cell Isolation and Molecular Analysis.- Enrichment and Detection of Circulating Tumor Cells and Other Rare Cell Populations by Microfluidic Filtration.- Detection and Enumeration of Circulating Tumor Cells with Invasive Phenotype.- Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures.- Detection of Gene-Rearrangements in Circulating Tumor Cells: Examples of ALK-, ROS1-, RET-Rearrangements in Non-Small-Cell Lung Cancer and ERG-Rearrangements in Prostate Cancer.- Enrichment, Isolation, and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells.- Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells.